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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PIPERONYL BUTOXIDE DISCONTINUED

PIPERONYL BUTOXIDE

ANTIPARASITIC
HEAD LICE
INHIBIT MONO-OXYGENASES AND NONSPECIFIC ESTERASES (PMID17192611)
PIPERONYL BUTOXIDE ITSELF HAS LIMITED INSECTICIDAL ACTIVITY. ITS SYNERGISTIC INTERACTION WITH PYRETHROIDS TAKES PLACES AT THE MICROSOMAL LEVEL. THE DETAILED MECHANISM HAS NOT BEEN FULLY CLARIFIED.

TOPICAL MONO-OXYGENASE
ESTERASE

Cytochrome P450 E0V9R7 (E0V9R7_PEDHC)EMA

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