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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TETRACAINE
| TETRACAINE |
CARDIOVASCULAR | TOPICAL OPHTHALMIC NASAL | Cmax NOT MEASURABLE PPB 75 PERCENT | SODIUM CHANNEL PDB 4OMW (CRYSTAL STRUCTURE OF GOAT BETA-LACTOGLOBULIN (ORTHORHOMBIC FORM)) LIGAND CODE = TE4 (link to the list of PDB complexes) Download experimental 3D coordinates of TE4 with added hydrogens | SODIUM CHANNEL ALPHA SUBUNIT BLOCKER CHEMBL2331043 SODIUM CHANNEL ALPHA SUBUNIT P35498 SODIUM CHANNEL PROTEIN TYPE 1 SUBUNIT ALPHA HOMO SAPIENS ION CHANNEL VGC VG NA | EMA | |||
