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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| EMEDASTINE DISCONTINUED
| EMEDASTINE | ALLERGIC CONJUNCTIVITIS | OPHTHALMIC | Cmax 1.6 NANOMOLAR (MAXIMUM QUANTIFIED) HT 3.5 HOUR SOLUBILITY WATER SOLUBLE FINE POWDER | HISTAMINE H1 RECEPTOR (KI=1.3 NANOMOLAR) | HISTAMINE H1 RECEPTOR ANTAGONIST CHEMBL231 HISTAMINE H1 RECEPTOR P35367 HISTAMINE H1 RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR HISTAMINE RECEPTOR | EMA | |||
