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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PRAMIPEXOLE
| PRAMIPEXOLE | NERVOUS SYSTEM | ORAL | F 90 PERCENT VD 500 LITER PPB 15 PERCENT Cl 43.3 LITER / HOUR (EQN) HT 8 HOUR SOLUBILITY 20 PERCENT IN WATER | D3 DOPAMINE RECEPTOR PDB 7CMU (DOPAMINE RECEPTOR D3R-GI-PRAMIPEXOLE COMPLEX) LIGAND CODE = G6L (link to the list of PDB complexes) Download experimental 3D coordinates of G6L with added hydrogens | D2-LIKE DOPAMINE RECEPTOR AGONIST CHEMBL2331075 D2-LIKE DOPAMINE RECEPTOR P14416 D(2) DOPAMINE RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR DOPAMINE RECEPTOR | EMA | |||
