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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| GUANETHIDINE DISCONTINUED
| GUANETHIDINE |
CARDIOVASCULAR | ORAL | Cmax 40 NANOMOLAR (10-50 MILLIGRAM / DAY) HT SEVERAL DAYS | NITRIC OXIDE SYNTHASE (PMID10889350) | NOREPINEPHRINE TRANSPORTER SUBSTRATE CHEMBL222 NOREPINEPHRINE TRANSPORTER P23975 SODIUM-DEPENDENT NORADRENALINE TRANSPORTER HOMO SAPIENS TRANSPORTER ELECTROCHEMICAL SLC SLC06 | EMA | |||
