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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PRIMAQUINE
| PRIMAQUINE | ANTIPARASITIC | ORAL | Cmax 16 NANOMOLAR (15 MILLIGRAM / DAY , PMID3542534) VD 292 LITER Cl 37.6 LITER / HOUR HT 5.6 HOUR | PDB 4FGJ (OXIDIZED QUINONE REDUCTASE 2 IN COMPLEX WITH PRIMAQUINE) LIGAND CODE = 1PQ (link to the list of PDB complexes) Download experimental 3D coordinates of 1PQ with added hydrogens | Sodium-dependent serotonin transporter P31645 (SC6A4_HUMAN) | EMA | |||
