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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LOMEFLOXACIN DISCONTINUED
| LOMEFLOXACIN | ANTIBACTERIAL | ORAL | Cmax 9.1 MICROMOLAR (400 MG) F 97 PERCENT VD 97.3 LITER (EQN) PPB 10 PERCENT Cl 8.7 LITER / HOUR HT 7.75 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN WATER | DNA GYRASE DNA TOPOISOMERASE | BACTERIAL DNA GYRASE INHIBITOR CHEMBL2311224 BACTERIAL DNA GYRASE P0AES4 DNA GYRASE SUBUNIT A BACTERIA ENZYME ISOMERASE | EMA | |||
