| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ONDANSETRON
| ONDANSETRON | METABOLISM | INJECTION ORAL | Cmax 0.34 MICROMOLAR VD 107 LITER (65 KILOGRAM) PPB 73 PERCENT Cl 24.7 LITER / HOUR (65 KILOGRAM) HT 3.5 HOUR SOLUBILITY SOLUBLE IN WATER | 5-HYDROXYTRYPTAMINE 3 RECEPTOR | SEROTONIN 3A (5-HT3A) RECEPTOR ANTAGONIST CHEMBL1899 SEROTONIN 3A (5-HT3A) RECEPTOR P46098 5-HYDROXYTRYPTAMINE RECEPTOR 3A HOMO SAPIENS ION CHANNEL LGIC 5HT3 | EMA | |||
