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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LEVOCETIRIZINE
| LEVOCETIRIZINE CETIRIZINE | RESPIRATORY | ORAL OPHTHALMIC INTRAVENOUS | Cmax 0.79 MICROMOLAR Tmax 2.2 HOUR VD 26 LITER (65 KILOGRAM) PPB 91 PERCENT Cl 2.4 LITER / HOUR (65 KILOGRAM) HT 8 HOUR SOLUBILITY VERY SOLUBLE IN WATER | HISTAMINE H1 RECEPTOR PDB 5DQF (HORSE SERUM ALBUMIN (ESA) IN COMPLEX WITH CETIRIZINE) LIGAND CODE = LCR (link to the list of PDB complexes) Download experimental 3D coordinates of LCR with added hydrogens | MULTIDRUG RESISTANCE PROTEIN 1 P08183 MULTIDRUG RESISTANCE PROTEIN 1 HOMO SAPIENS TRANSPORTER NTPASE ATP BINDING CASSETTE MDR | EMA | |||
