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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FOSFOMYCIN
| FOSFOMYCIN | NATURAL MOLECULE (link)
ANTIINFECTIVES | ORAL | Cmax 189 MICROMOLAR F 37 PERCENT VD 136.1 LITER PPB 0 PERCENT Cl 16.9 LITER / HOUR HT 5.7 HOUR SOLUBILITY SOLUBLE IN WATER | ENOLPYRUVYL TRANSFERASE PDB 4IR0 (CRYSTAL STRUCTURE OF METALLOTHIOL TRANSFERASE FOSB 2 FROM BACILLUS ANTHRACIS STR. AMES) LIGAND CODE = FCN (link to the list of PDB complexes) Download experimental 3D coordinates of FCN with added hydrogens | UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE INHIBITOR CHEMBL1984 UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE P0A749 UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE ESCHERICHIA COLI K-12 ENZYME TRANSFERASE | EMA | |||
