| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CLARITHROMYCIN
| CLARITHROMYCIN |
ANTIINFECTIVES | ORAL | Cmax 5 MICROMOLAR F 50 PERCENT VD 97.5 LITER (65 KILOGRAM) PPB 77 PERCENT Cl 28.5 LITER / HOUR (65 KILOGRAM) HT 6 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | 50S RIBOSOMAL PROTEIN PDB 5IGW (MACROLIDE 2'-PHOSPHOTRANSFERASE TYPE II - COMPLEX WITH GDP AND CLARITHROMYCIN) LIGAND CODE = CTY (link to the list of PDB complexes) Download experimental 3D coordinates of CTY with added hydrogens | BACTERIAL 70S RIBOSOME INHIBITOR CHEMBL2363135 BACTERIAL 70S RIBOSOME 23S RIBOSOMAL RNA BACTERIA | EMA | |||
