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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| VANCOMYCIN
| VANCOMYCIN |
ANTIINFECTIVES | ORAL INJECTION INTRAVENOUS | Cmax 0.45 MICROMOLAR F POORLY ABSORBED VD 35.1 LITER (65 KILOGRAM) PPB 30 PERCENT Cl 5.07 LITER / HOUR (65 KILOGRAM) HT 6.5 HOUR | DNA PDB 1PNV (TDP-EPI-VANCOSAMINYLTRANSFERASE GTFA FROM AMYCOLATOPSIS ORIENTALIS) | PEPTIDOGLYCAN INHIBITOR CHEMBL3041361 PEPTIDOGLYCAN BACTERIA | EMA | |||
