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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CILASTATIN
| CILASTATIN | ANTIINFECTIVES | INTRAVENOUS INTRAMUSCULAR INJECTION | Cmax 92 MICROMOLAR F 95 PERCENT VD 9.75 LITER (65 KILOGRAM) PPB 40 PERCENT Cl 8.97 LITER / HOUR (65 KILOGRAM) HT 0.86 HOUR SOLUBILITY VERY SOLUBLE IN WATER | DIPEPTIDASE 1 DEHYDROPEPTIDASE I PDB 1ITU (HUMAN RENAL DIPEPTIDASE) | RENAL DIPEPTIDASE INHIBITOR CHEMBL1989 RENAL DIPEPTIDASE P16444 DIPEPTIDASE 1 HOMO SAPIENS ENZYME PROTEASE METALLO MJ M19 | EMA | |||
