e-Drug3D

81

cas 599-79-1

CLASS

METABOLISM
ANTIINFLAMMATORY
TREATMENT OF MILD TO MODERATE ULCERATIVE COLITIS
INTERFERENCE WITH TETRAHYDROBIOPTERIN METABOLISM (BINDS SEPIAPTERIN REDUCTASE (SPR)(PMID21499265))

ROUTE (list)

ORAL

PK parameters

F 15 PERCENT
Tmax 6 HOUR
VD 7.5 LITER
Cl 1 LITER / HOUR
PPB 99.3 PERCENT
t1/2 7.6 HOUR

MW 397.39
NB_atoms 28
XLogP 0.47
PSA 124.072
NB_HD 2
NB_HA 9
fsp3 0.00
Lipinski(0=no;1=yes) 1

FDA
NDA 088052 (pdf not found) INN (SULFASALAZINE) SULFASALAZINE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089339 (pdf not found) INN (SULFASALAZINE) SULFASALAZINE (SUPERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 007073 (label) INN (SULFASALAZINE) AZULFIDINE (PFIZER) APPROVAL= AP YEAR= 1950
NDA 080197 (pdf not found) INN (SULFASALAZINE) SULFASALAZINE (CHARTWELL) APPROVAL= AP YEAR= 1973
NDA 083450 (pdf not found) INN (SULFASALAZINE) S.A.S.-500 (SOLVAY) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 084964 (pdf not found) INN (SULFASALAZINE) SULFASALAZINE (WATSON LABS) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 085828 (pdf not found) INN (SULFASALAZINE) SULFASALAZINE (WATSON LABS) APPROVAL= AP YEAR= 1977
NDA 018605 (pdf not found) INN (SULFASALAZINE) AZULFIDINE (PHARMACIA AND UPJOHN) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 086983 (pdf not found) INN (SULFASALAZINE) AZULFIDINE (PHARMACIA AND UPJOHN) APPROVAL= AP YEAR= 1980 OBSOLETE
NDA 087197 (pdf not found) INN (SULFASALAZINE) SULFASALAZINE (WATSON LABS) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 086184 (pdf not found) INN (SULFASALAZINE) SULFASALAZINE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 089590 (pdf not found) INN (SULFASALAZINE) SULFASALAZINE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 020465 (label) INN (SULFASALAZINE) AZULFIDINE (PHARMACIA AND UPJOHN) APPROVAL= AP YEAR= 1996 NEWAPPLICATION
NDA 021243 (label) INN (SULFASALAZINE) AZULFIDINE EN-TABS (PHARMACIA UPJOHN) APPROVAL= AP YEAR= 2000 NEWAPPLICATION
NDA 040349 (pdf not found) INN (SULFASALAZINE) SULFASALAZINE (NUVO PHARMS INC) APPROVAL= AP YEAR= 2002
NDA 075339 (pdf not found) INN (SULFASALAZINE) SULFASALAZINE (NUVO PHARMS INC) APPROVAL= AP YEAR= 2002
NDA 219046 (pdf not found) INN (SULFASALAZINE) SULFASALAZINE (RISING) APPROVAL= AP YEAR= 2025