e-Drug3D

2165

TEBIPENEM

INN
TEBIPENEM

cas 161715-21-5

CLASS

ANTIINFECTIVES
PENEM ANTIBACTERIAL PRODRUG FOR THE TREATMENT OF COMPLICATED URINARY TRACT INFECTIONS (CUTI)

ROUTE (list)

ATC code

J01DH06

PK parameters

Tmax 1.0 HOUR
VD 66.4 LITER
Cl 34.2 LITER / HOUR
PPB 42 PERCENT
t1/2 1.6 HOUR

Target

TARGET PENICILLIN-BINDING PROTEINS (PBPS)

PDB
4QB8 (CRYSTAL STRUCTURE OF BETA-LACTAMASE FROM M.TUBERCULOSIS FORMING MICHAELIS MENTEN WITH TEBIPENEM)

Download experimental 3D coordinates of 1TE with added hydrogens

Unknown

Download SDF file

(1R,5S,6S)-6-(1(R)-Hydroxyethyl)-1-methyl-2-(1-(2-thiazolin-2-yl)azetidin-3-ylsulfanyl)-1-carba-2-penem-3-carboxylic acid

Formula:
C16H21N3O4S2

Calculated chemical properties:

MW 382.49
NB_atoms 25
XLogP -0.67
PSA 93.729
NB_HD 1
NB_HA 7
fsp3 0.69
Lipinski(0=no;1=yes) 1

FDA
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