| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TIOCONAZOLE
| TIOCONAZOLE | DERMATOLOGICALS | TOPICAL VAGINAL | CYTOCHROME P450 51 PDB 7LYX (CRYSTAL STRUCTURE OF HUMAN CYP8B1 IN COMPLEX WITH (S)-TIOCONAZOLE) LIGAND CODE = YHM (link to the list of PDB complexes) Download experimental 3D coordinates of YHM with added hydrogens | Lanosterol 14-alpha demethylase UNIPROT P10613 ERG11 more at DrugCentral | EMA | ||||
