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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DACARBAZINE

DACARBAZINE


ATC L01AX04

ANTINEOPLASTIC
ALKYLATING
HYPOTHESIS OF INHIBITION OF DNA SYNTHESIS BY ACTING AS A PURINE ANALOG

INJECTION

VD 78 LITER (65 KILOGRAM)

PPB 0 PERCENT

Cl 10.1 LITER / HOUR (65 KILOGRAM)

HT 6.2 HOUR

DNA

DNA INHIBITOR CHEMBL2311221 DNA HOMO SAPIENSANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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