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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
M TRAMADOL (is an active metabolite)

TRAMADOL


ATC N02AX02
ATC N02AX52
ATC N02AJ14
ATC N02AJ15
ATC N02AJ13

NERVOUS SYSTEM
NARCOTICS
CENTRALLY ACTING OPIOID ANALGESIC
MU OPIOID RECEPTOR AGONIST

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Cmax 441 NANOMOLAR

Tmax 2.4 HOUR

HT 7.4 HOUR

MU-TYPE OPIOID RECEPTOR

MU OPIOID RECEPTOR AGONIST CHEMBL233 MU OPIOID RECEPTOR P35372 MU-TYPE OPIOID RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE OPIOID RECEPTORANSM (in French)

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