e-Drug3D

993

cas 79-57-2

CLASS

ANTIINFECTIVES
ANTIFUNGAL
ANTIBIOTIC
ANTIBACTERIAL
TETRACYCLINES

ROUTE (list)

ORAL INJECTION VAGINAL OPHTHALMIC OTIC

PK parameters

VD 110 LITER (65 KILOGRAM)
Cl 7.8 LITER / HOUR (65 KILOGRAM)
PPB 10 PERCENT
t1/2 10 HOUR

TARGET 30S RIBOSOMAL PROTEIN

PDB
2XPW (TETR(D) IN COMPLEX WITH OXYTETRACYCLINE AND MAGNESIUM.)

Ligand code = OTC (link to the list of PDB complexes)

Download experimental 3D coordinates of OTC with added hydrogens

MW 460.43
NB_atoms 33
XLogP -1.24
PSA 187.756
NB_HD 8
NB_HA 11
fsp3 0.41
Lipinski(0=no;1=yes) 0

FDA
NDA 050287 (pdf not found) INN (OXYTETRACYCLINE) TERRAMYCIN (PFIZER) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060586 (pdf not found) INN (OXYTETRACYCLINE HYDROCHLORIDE) TERRAMYCIN (PFIZER) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060595 (pdf not found) INN (OXYTETRACYCLINE CALCIUM) TERRAMYCIN (PFIZER) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060634 (pdf not found) INN (OXYTETRACYCLINE HYDROCHLORIDE) OXYTETRACYCLINE HYDROCHLORIDE (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061009 (pdf not found) INN (OXYTETRACYCLINE HYDROCHLORIDE ; POLYMYXIN B SULFATE) TERRAMYCIN-POLYMYXIN (PFIZER) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061841 (pdf not found) INN (OXYTETRACYCLINE HYDROCHLORIDE ; POLYMYXIN B SULFATE) TERRAMYCIN W/ POLYMYXIN (PFIZER) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 050286 (pdf not found) INN (OXYTETRACYCLINE HYDROCHLORIDE) TERRAMYCIN (PFIZER) APPROVAL= AP YEAR= 1964 DISCONTINUED
NDA 060567 (pdf not found) INN (LIDOCAINE HYDROCHLORIDE ; OXYTETRACYCLINE) TERRAMYCIN (PFIZER) APPROVAL= AP YEAR= 1964 DISCONTINUED
NDA 060869 (pdf not found) INN (OXYTETRACYCLINE HYDROCHLORIDE) OXYTETRACYCLINE HYDROCHLORIDE (PROTER) APPROVAL= AP YEAR= 1964 DISCONTINUED
NDA 061015 (pdf not found) INN (OXYTETRACYCLINE HYDROCHLORIDE ; POLYMYXIN B SULFATE) TERRAMYCIN W/ POLYMYXIN B SULFATE (CASPER PHARMA LLC) APPROVAL= AP YEAR= 1965 DISCONTINUED
NDA 060179 (pdf not found) INN (OXYTETRACYCLINE HYDROCHLORIDE) OXY-KESSO-TETRA (FERRANTE) APPROVAL= AP YEAR= 1967 DISCONTINUED
NDA 060760 (pdf not found) INN (OXYTETRACYCLINE HYDROCHLORIDE) OXYTETRACYCLINE HYDROCHLORIDE (IMPAX LABS) APPROVAL= AP YEAR= 1967 DISCONTINUED
NDA 060770 (pdf not found) INN (OXYTETRACYCLINE HYDROCHLORIDE) OXYTETRACYCLINE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 1967 DISCONTINUED
NDA 061016 (pdf not found) INN (HYDROCORTISONE ACETATE ; OXYTETRACYCLINE HYDROCHLORIDE) TERRA-CORTRIL (PFIZER) APPROVAL= AP YEAR= 1969 DISCONTINUED