e-Drug3D

984

cas 18323-44-9

CLASS

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
PROTEIN SYNTHESIS INHIBITORS
ANTIMALARIALS

ROUTE (list)

ORAL

PK parameters

VD 51.3 LITER (65 KILOGRAM)
Cl 17.5 LITER / HOUR (65 KILOGRAM)
PPB 94 PERCENT
t1/2 2.4 HOUR

TARGET 50S RIBOSOMAL SUBUNIT

PDB
3JZ0 (LINB COMPLEXED WITH CLINDAMYCIN AND AMPCPP)

Ligand code = CLY (link to the list of PDB complexes)

Download experimental 3D coordinates of CLY with added hydrogens

MW 424.98
NB_atoms 27
XLogP 0.39
PSA 93.934
NB_HD 4
NB_HA 7
fsp3 0.94
Lipinski(0=no;1=yes) 1

FDA
NDA 061809 (pdf not found) INN (CLINDAMYCIN HYDROCHLORIDE) CLEOCIN (PHARMACIA AND UPJOHN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 050162 (label) INN (CLINDAMYCIN HYDROCHLORIDE) CLEOCIN HYDROCHLORIDE (PFIZER) APPROVAL= AP YEAR= 1970
NDA 063027 (pdf not found) INN (CLINDAMYCIN HYDROCHLORIDE) CLINDAMYCIN HYDROCHLORIDE (TEVA) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 063029 (pdf not found) INN (CLINDAMYCIN HYDROCHLORIDE) CLINDAMYCIN HYDROCHLORIDE (COSETTE) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 063082 (pdf not found) INN (CLINDAMYCIN HYDROCHLORIDE) CLINDAMYCIN HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 063083 (pdf not found) INN (CLINDAMYCIN HYDROCHLORIDE) CLINDAMYCIN HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 065061 (pdf not found) INN (CLINDAMYCIN HYDROCHLORIDE) CLINDAMYCIN HYDROCHLORIDE (SUN PHARM INDS LTD) APPROVAL= AP YEAR= 2001
NDA 065194 (pdf not found) INN (CLINDAMYCIN HYDROCHLORIDE) CLINDAMYCIN HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2004
NDA 065217 (pdf not found) INN (CLINDAMYCIN HYDROCHLORIDE) CLINDAMYCIN HYDROCHLORIDE (ZYDUS PHARMS USA) APPROVAL= AP YEAR= 2005
NDA 065242 (pdf not found) INN (CLINDAMYCIN HYDROCHLORIDE) CLINDAMYCIN HYDROCHLORIDE (LANNETT) APPROVAL= AP YEAR= 2005
NDA 065243 (pdf not found) INN (CLINDAMYCIN HYDROCHLORIDE) CLINDAMYCIN HYDROCHLORIDE (CHARTWELL MOLECULAR) APPROVAL= AP YEAR= 2005
NDA 065442 (pdf not found) INN (CLINDAMYCIN HYDROCHLORIDE) CLINDAMYCIN HYDROCHLORIDE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2009
NDA 091225 (pdf not found) INN (CLINDAMYCIN HYDROCHLORIDE) CLINDAMYCIN HYDROCHLORIDE (PHARMOBEDIENT) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 207402 (pdf not found) INN (CLINDAMYCIN HYDROCHLORIDE) CLINDAMYCIN HYDROCHLORIDE (MICRO LABS) APPROVAL= AP YEAR= 2018
NDA 216957 (pdf not found) INN (CLINDAMYCIN HYDROCHLORIDE) CLINDAMYCIN HYDROCHLORIDE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2023