e-Drug3D
982
PENICILLIN V
INN
PENICILLIN V
cas 87-08-1
CLASS
ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
PENICILLINS
ROUTE (list)
ORAL
ATC code
J01CE02
PK parameters
VD 26.6 LITER (65 KILOGRAM)
Cl 26.5 LITER / HOUR (65 KILOGRAM)
PPB 80 PERCENT
t1/2 0.84 HOUR
TARGET BETA-LACTAMASE
PENICILLIN-BINDING PROTEINS 1A/1B
PENICILLIN-BINDING PROTEINS 1A/1B
PDB
2Z71 (STRUCTURE OF TRUNCATED MUTANT CYS1GLY OF PENICILLIN V ACYLASE FROM BACILLUS SPHAERICUS CO-CRYSTALLIZED WITH PENICILLIN V)
Ligand code = PNV (link to the list of PDB complexes)
Download experimental 3D coordinates of PNV with added hydrogens
Bacterial penicillin-binding protein UNIPROT P02918 mrcA
Formula:
C16H18N2O5S
Calculated chemical properties:
MW 349.39
NB_atoms 24
XLogP -0.64
PSA 96.13
NB_HD 1
NB_HA 7
fsp3 0.44
Lipinski(0=no;1=yes) 1
NB_atoms 24
XLogP -0.64
PSA 96.13
NB_HD 1
NB_HA 7
fsp3 0.44
Lipinski(0=no;1=yes) 1
FDA
NDA 060002 (pdf not found) INN (PENICILLIN V) V-CILLIN (LILLY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060003 (pdf not found) INN (PENICILLIN V POTASSIUM) V-CILLIN K (LILLY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060007 (pdf not found) INN (PENICILLIN V POTASSIUM) PEN-VEE K (WYETH AYERST) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060134 (pdf not found) INN (PENICILLIN V POTASSIUM) LEDERCILLIN VK (LEDERLE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060136 (pdf not found) INN (PENICILLIN V POTASSIUM) LEDERCILLIN VK (LEDERLE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060518 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (IVAX SUB TEVA PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061149 (pdf not found) INN (PENICILLIN V POTASSIUM) BETAPEN-VK (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061150 (pdf not found) INN (PENICILLIN V POTASSIUM) BETAPEN-VK (BRISTOL) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061164 (pdf not found) INN (PENICILLIN V POTASSIUM) VEETIDS '250' (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061206 (pdf not found) INN (PENICILLIN V POTASSIUM) VEETIDS '125' (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061530 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (MYLAN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061571 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061651 (pdf not found) INN (PENICILLIN V POTASSIUM) UTICILLIN VK (PHARMACIA AND UPJOHN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062001 (pdf not found) INN (PENICILLIN V POTASSIUM) PENAPAR-VK (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062002 (pdf not found) INN (PENICILLIN V POTASSIUM) PENAPAR-VK (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062153 (pdf not found) INN (PENICILLIN V POTASSIUM) VEETIDS '125' (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062156 (pdf not found) INN (PENICILLIN V POTASSIUM) VEETIDS '500' (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060006 (pdf not found) INN (PENICILLIN V POTASSIUM) PEN-VEE K (WYETH AYERST) APPROVAL= AP YEAR= 1958 DISCONTINUED
NDA 060004 (pdf not found) INN (PENICILLIN V POTASSIUM) V-CILLIN K (LILLY) APPROVAL= AP YEAR= 1967 DISCONTINUED
NDA 060456 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN-VK (TEVA) APPROVAL= AP YEAR= 1968
NDA 060711 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN-VK (TEVA) APPROVAL= AP YEAR= 1968
NDA 061410 (pdf not found) INN (PENICILLIN V POTASSIUM) VEETIDS (APOTHECON) APPROVAL= AP YEAR= 1971 DISCONTINUED
NDA 061528 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (BELCHER PHARMS) APPROVAL= AP YEAR= 1971 DISCONTINUED
NDA 061529 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (BELCHER PHARMS) APPROVAL= AP YEAR= 1971 DISCONTINUED
NDA 061624 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (MYLAN) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 061815 (pdf not found) INN (PENICILLIN V POTASSIUM) PFIZERPEN VK (PFIZER) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 061836 (pdf not found) INN (PENICILLIN V POTASSIUM) PFIZERPEN VK (PFIZER) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 061758 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (PUREPAC PHARM) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 062270 (pdf not found) INN (PENICILLIN V POTASSIUM) BEEPEN-VK (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 062273 (pdf not found) INN (PENICILLIN V POTASSIUM) BEEPEN-VK (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 062935 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (CHARTWELL RX) APPROVAL= AP YEAR= 1988
NDA 062936 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (CHARTWELL RX) APPROVAL= AP YEAR= 1988
NDA 062981 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (CHARTWELL RX) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 061411 (pdf not found) INN (PENICILLIN V POTASSIUM) VEETIDS (APOTHECON) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 064071 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (SANDOZ) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 065435 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2008
NDA 090549 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (HIKMA PHARMS) APPROVAL= AP YEAR= 2013
NDA 060002 (pdf not found) INN (PENICILLIN V) V-CILLIN (LILLY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060003 (pdf not found) INN (PENICILLIN V POTASSIUM) V-CILLIN K (LILLY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060007 (pdf not found) INN (PENICILLIN V POTASSIUM) PEN-VEE K (WYETH AYERST) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060134 (pdf not found) INN (PENICILLIN V POTASSIUM) LEDERCILLIN VK (LEDERLE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060136 (pdf not found) INN (PENICILLIN V POTASSIUM) LEDERCILLIN VK (LEDERLE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060518 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (IVAX SUB TEVA PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061149 (pdf not found) INN (PENICILLIN V POTASSIUM) BETAPEN-VK (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061150 (pdf not found) INN (PENICILLIN V POTASSIUM) BETAPEN-VK (BRISTOL) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061164 (pdf not found) INN (PENICILLIN V POTASSIUM) VEETIDS '250' (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061206 (pdf not found) INN (PENICILLIN V POTASSIUM) VEETIDS '125' (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061530 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (MYLAN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061571 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061651 (pdf not found) INN (PENICILLIN V POTASSIUM) UTICILLIN VK (PHARMACIA AND UPJOHN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062001 (pdf not found) INN (PENICILLIN V POTASSIUM) PENAPAR-VK (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062002 (pdf not found) INN (PENICILLIN V POTASSIUM) PENAPAR-VK (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062153 (pdf not found) INN (PENICILLIN V POTASSIUM) VEETIDS '125' (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062156 (pdf not found) INN (PENICILLIN V POTASSIUM) VEETIDS '500' (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060006 (pdf not found) INN (PENICILLIN V POTASSIUM) PEN-VEE K (WYETH AYERST) APPROVAL= AP YEAR= 1958 DISCONTINUED
NDA 060004 (pdf not found) INN (PENICILLIN V POTASSIUM) V-CILLIN K (LILLY) APPROVAL= AP YEAR= 1967 DISCONTINUED
NDA 060456 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN-VK (TEVA) APPROVAL= AP YEAR= 1968
NDA 060711 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN-VK (TEVA) APPROVAL= AP YEAR= 1968
NDA 061410 (pdf not found) INN (PENICILLIN V POTASSIUM) VEETIDS (APOTHECON) APPROVAL= AP YEAR= 1971 DISCONTINUED
NDA 061528 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (BELCHER PHARMS) APPROVAL= AP YEAR= 1971 DISCONTINUED
NDA 061529 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (BELCHER PHARMS) APPROVAL= AP YEAR= 1971 DISCONTINUED
NDA 061624 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (MYLAN) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 061815 (pdf not found) INN (PENICILLIN V POTASSIUM) PFIZERPEN VK (PFIZER) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 061836 (pdf not found) INN (PENICILLIN V POTASSIUM) PFIZERPEN VK (PFIZER) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 061758 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (PUREPAC PHARM) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 062270 (pdf not found) INN (PENICILLIN V POTASSIUM) BEEPEN-VK (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 062273 (pdf not found) INN (PENICILLIN V POTASSIUM) BEEPEN-VK (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 062935 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (CHARTWELL RX) APPROVAL= AP YEAR= 1988
NDA 062936 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (CHARTWELL RX) APPROVAL= AP YEAR= 1988
NDA 062981 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (CHARTWELL RX) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 061411 (pdf not found) INN (PENICILLIN V POTASSIUM) VEETIDS (APOTHECON) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 064071 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (SANDOZ) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 065435 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2008
NDA 090549 (pdf not found) INN (PENICILLIN V POTASSIUM) PENICILLIN V POTASSIUM (HIKMA PHARMS) APPROVAL= AP YEAR= 2013