e-Drug3D

981

cas 61-33-6

CLASS

ANTIINFECTIVES
ANTIBACTERIAL
PENICILLINS
ANTIBIOTIC

ROUTE (list)

ORAL INJECTION INTRAMUSCULAR INTRAVENOUS

PK parameters

VD 15 LITER (65 KILOGRAM)
Cl 24.8 LITER / HOUR (65 KILOGRAM)
PPB 60 PERCENT
t1/2 0.7 HOUR

TARGET PENICILLIN-BINDING PROTEINS 1A/1B

PDB
1UOB (DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH 2-OXOGLUTARATE AND PENICILLIN G)

Ligand code = PNN (link to the list of PDB complexes)

Download experimental 3D coordinates of PNN with added hydrogens

MW 333.39
NB_atoms 23
XLogP -0.47
PSA 86.077
NB_HD 1
NB_HA 6
fsp3 0.44
Lipinski(0=no;1=yes) 1

FDA
NDA 050128 (pdf not found) INN (PENICILLIN G BENZATHINE) BICILLIN (WYETH AYERST) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060073 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (IVAX SUB TEVA PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060093 (pdf not found) INN (PENICILLIN G PROCAINE) DURACILLIN A.S. (LILLY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060362 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060384 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (LILLY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060392 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060403 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (LILLY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060413 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (WYETH AYERST) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060601 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (LILLY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060752 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (MYLAN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060800 (pdf not found) INN (PENICILLIN G PROCAINE) PENICILLIN G PROCAINE (CONSOLIDATED PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060806 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (CONSOLIDATED PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061046 (pdf not found) INN (PENICILLIN G SODIUM) PENICILLIN G SODIUM (PHARMACIA AND UPJOHN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061051 (pdf not found) INN (PENICILLIN G SODIUM) PENICILLIN G SODIUM (COPANOS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061588 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061740 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061935 (pdf not found) INN (PENICILLIN G SODIUM) PENICILLIN G SODIUM (BRISTOL MYERS SQUIBB) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062003 (label) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062029 (pdf not found) INN (PENICILLIN G PROCAINE) PENICILLIN G PROCAINE (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062149 (pdf not found) INN (PENICILLIN G POTASSIUM) PENTIDS '200' (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062155 (pdf not found) INN (PENICILLIN G POTASSIUM) PENTIDS '200' (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060074 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (PFIZER) APPROVAL= AP YEAR= 1947 DISCONTINUED
NDA 060075 (pdf not found) INN (PENICILLIN G POTASSIUM) PFIZERPEN G (PFIZER) APPROVAL= AP YEAR= 1948 DISCONTINUED
NDA 060099 (pdf not found) INN (PENICILLIN G PROCAINE) PENICILLIN G PROCAINE (PFIZER) APPROVAL= AP YEAR= 1948 DISCONTINUED
NDA 060101 (pdf not found) INN (PENICILLIN G PROCAINE) PENICILLIN G PROCAINE (KING PHARMS LLC) APPROVAL= AP YEAR= 1948
NDA 060286 (pdf not found) INN (PENICILLIN G PROCAINE) PFIZERPEN-AS (PFIZER) APPROVAL= AP YEAR= 1950 DISCONTINUED
NDA 050126 (pdf not found) INN (PENICILLIN G BENZATHINE) BICILLIN (WYETH AYERST) APPROVAL= AP YEAR= 1951 DISCONTINUED
NDA 060587 (pdf not found) INN (PENICILLIN G POTASSIUM) PFIZERPEN G (PFIZER) APPROVAL= AP YEAR= 1951 DISCONTINUED
NDA 050141 (label) INN (PENICILLIN G BENZATHINE) BICILLIN L-A (KING PHARMS LLC) APPROVAL= AP YEAR= 1952
NDA 060014 (pdf not found) INN (PENICILLIN G BENZATHINE) PERMAPEN (CASPER PHARMA LLC) APPROVAL= AP YEAR= 1952 DISCONTINUED
NDA 050138 (label) INN (PENICILLIN G BENZATHINE ; PENICILLIN G PROCAINE) BICILLIN C-R (KING PHARMS LLC) APPROVAL= AP YEAR= 1953
NDA 050131 (pdf not found) INN (PENICILLIN G BENZATHINE) BICILLIN L-A (WYETH AYERST) APPROVAL= AP YEAR= 1958 DISCONTINUED
NDA 060307 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN (TEVA) APPROVAL= AP YEAR= 1964 DISCONTINUED
NDA 060657 (pdf not found) INN (PENICILLIN G POTASSIUM) PFIZERPEN (PFIZER) APPROVAL= AP YEAR= 1968
NDA 050114 (label) INN (BENZYLPENICILLOYL POLYLYSINE) PRE-PEN (ALLERQUEST) APPROVAL= AP YEAR= 1974 NEWMOLECULARENTITY
NDA 060306 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (TEVA) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 060781 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (MYLAN) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 062991 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (WATSON LABS INC) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 063014 (pdf not found) INN (PENICILLIN G SODIUM) PENICILLIN G SODIUM (WATSON LABS INC) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 050638 (label) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM IN PLASTIC CONTAINER (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1990
NDA 065068 (label) INN (PENICILLIN G SODIUM) PENICILLIN G SODIUM (SANDOZ) APPROVAL= AP YEAR= 2001
NDA 065079 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (SANDOZ) APPROVAL= AP YEAR= 2002
NDA 065149 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (HQ SPECLT PHARMA) APPROVAL= AP YEAR= 2009
NDA 065448 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (ISTITUTO BIO ITA SPA) APPROVAL= AP YEAR= 2009
NDA 205043 (pdf not found) INN (PENICILLIN G POTASSIUM) PENICILLIN G POTASSIUM (ACS DOBFAR SPA) APPROVAL= AP YEAR= 2018