e-Drug3D

974

cas 56-75-7

CLASS

ANTIINFECTIVES
ANTIRICKETTSIAL
ANTIBIOTIC
ANTIBACTERIAL
PROTEIN SYNTHESIS INHIBITORS
PRODUCT BY STREPTOMYCES VENEZUELAE

ROUTE (list)

OPHTHALMIC INJECTION TOPICAL OTIC ORAL

PK parameters

VD 61 LITER (65 KILOGRAM)
Cl 9.3 LITER / HOUR (65 KILOGRAM)
PPB 66 PERCENT
t1/2 4.6 HOUR

TARGET 50S RIBOSOMAL PROTEIN

PDB
4V7W (STRUCTURE OF THE THERMUS THERMOPHILUS RIBOSOME COMPLEXED WITH CHLORAMPHENICOL)

Ligand code = CLM (link to the list of PDB complexes)

Download experimental 3D coordinates of CLM with added hydrogens

MW 323.13
NB_atoms 20
XLogP 0
PSA 101.432
NB_HD 3
NB_HA 6
fsp3 0.36
Lipinski(0=no;1=yes) 1

FDA
NDA 050153 (pdf not found) INN (CHLORAMPHENICOL) CHLOROMYCETIN (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 050183 (pdf not found) INN (CHLORAMPHENICOL) CHLOROMYCETIN (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 050203 (label) INN (CHLORAMPHENICOL ; POLYMYXIN B SULFATE) CHLOROMYXIN (PARKE DAVIS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060058 (pdf not found) INN (CHLORAMPHENICOL) AMPHICOL (FERRANTE) APPROVAL= AP YEAR= 0 DISCONTINUED OBSOLETE
NDA 060132 (pdf not found) INN (CHLORAMPHENICOL SODIUM SUCCINATE) MYCHEL-S (ANGUS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061188 (pdf not found) INN (CHLORAMPHENICOL ; PREDNISOLONE) CHLOROPTIC-P S.O.P. (ALLERGAN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062278 (pdf not found) INN (CHLORAMPHENICOL SODIUM SUCCINATE) CHLORAMPHENICOL SODIUM SUCCINATE (GRUPPO LEPETIT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062406 (pdf not found) INN (CHLORAMPHENICOL SODIUM SUCCINATE) CHLORAMPHENICOL (ELKINS SINN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062437 (pdf not found) INN (CHLORAMPHENICOL) CHLOROFAIR (PHARMAFAIR) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062439 (pdf not found) INN (CHLORAMPHENICOL) CHLOROFAIR (PHARMAFAIR) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060591 (pdf not found) INN (CHLORAMPHENICOL) CHLOROMYCETIN (PARKEDALE) APPROVAL= AP YEAR= 1950 DISCONTINUED OBSOLETE
NDA 050143 (pdf not found) INN (CHLORAMPHENICOL) CHLOROMYCETIN (PARKEDALE) APPROVAL= AP YEAR= 1951 DISCONTINUED
NDA 050156 (pdf not found) INN (CHLORAMPHENICOL) CHLOROMYCETIN (PARKEDALE) APPROVAL= AP YEAR= 1951 DISCONTINUED
NDA 050202 (pdf not found) INN (CHLORAMPHENICOL ; HYDROCORTISONE ACETATE) CHLOROMYCETIN HYDROCORTISONE (PARKEDALE) APPROVAL= AP YEAR= 1953 DISCONTINUED
NDA 050205 (pdf not found) INN (CHLORAMPHENICOL) CHLOROMYCETIN (PARKEDALE) APPROVAL= AP YEAR= 1953 DISCONTINUED
NDA 050201 (pdf not found) INN (CHLORAMPHENICOL ; HYDROCORTISONE ACETATE ; POLYMYXIN B SULFATE) OPHTHOCORT (PARKEDALE) APPROVAL= AP YEAR= 1958 DISCONTINUED
NDA 050155 (label) INN (CHLORAMPHENICOL SODIUM SUCCINATE) CHLOROMYCETIN (PARKEDALE) APPROVAL= AP YEAR= 1959 DISCONTINUED
NDA 050294 (pdf not found) INN (CHLORAMPHENICOL ; DESOXYRIBONUCLEASE ; FIBRINOLYSIN) ELASE-CHLOROMYCETIN (PARKE DAVIS) APPROVAL= AP YEAR= 1964 DISCONTINUED
NDA 060851 (pdf not found) INN (CHLORAMPHENICOL) MYCHEL (ARMENPHARM) APPROVAL= AP YEAR= 1967 DISCONTINUED
NDA 050091 (label) INN (CHLORAMPHENICOL) CHLOROPTIC (ALLERGAN) APPROVAL= AP YEAR= 1968 DISCONTINUED
NDA 060133 (pdf not found) INN (CHLORAMPHENICOL) CHLORAMPHENICOL (ALTANA) APPROVAL= AP YEAR= 1968 DISCONTINUED
NDA 061187 (pdf not found) INN (CHLORAMPHENICOL) CHLOROPTIC S.O.P. (ALLERGAN) APPROVAL= AP YEAR= 1970 DISCONTINUED
NDA 061220 (pdf not found) INN (CHLORAMPHENICOL) OPHTHOCHLOR (PARKEDALE) APPROVAL= AP YEAR= 1970 DISCONTINUED
NDA 061645 (pdf not found) INN (CHLORAMPHENICOL) ECONOCHLOR (ALCON) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 061648 (pdf not found) INN (CHLORAMPHENICOL) ECONOCHLOR (ALCON) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 062247 (pdf not found) INN (CHLORAMPHENICOL) CHLORAMPHENICOL (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 062042 (pdf not found) INN (CHLORAMPHENICOL) CHLORAMPHENICOL (EPIC PHARMA LLC) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 062171 (pdf not found) INN (CHLORAMPHENICOL) OPTOMYCIN (OPTOPICS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 062365 (pdf not found) INN (CHLORAMPHENICOL SODIUM SUCCINATE) CHLORAMPHENICOL SODIUM SUCCINATE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 062628 (pdf not found) INN (CHLORAMPHENICOL) CHLORAMPHENICOL (ALCON) APPROVAL= AP YEAR= 1985 DISCONTINUED