e-Drug3D

949

cas 144598-75-4

CLASS

NERVOUS SYSTEM
ANTIPSYCHOTIC
SCHIZOPHRENIA
BENZISOXAZOLE DERIVATIVES
DOPAMINE D2 RECEPTOR ANTAGONIST
SEROTONIN TYPE 2 (5HT2A) RECEPTOR ANTAGONIST

ROUTE (list)

ORAL

PK parameters

Tmax 3 HOUR
VD 391 LITER
Cl 10.8 LITER / HOUR (EQN)
PPB 74 PERCENT
t1/2 25 HOUR

MW 426.49
NB_atoms 31
XLogP 3.08
PSA 78.557
NB_HD 1
NB_HA 7
fsp3 0.52
Lipinski(0=no;1=yes) 1

FDA
NDA 021999 (label) INN (PALIPERIDONE) INVEGA (JANSSEN PHARMS) APPROVAL= AP YEAR= 2006
NDA 022043 (label) INN (PALIPERIDONE) INVEGA (JANSSEN LP) APPROVAL= AP YEAR= 2007 NEWAPPLICATION
NDA 202645 (pdf not found) INN (PALIPERIDONE) PALIPERIDONE (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 203802 (pdf not found) INN (PALIPERIDONE) PALIPERIDONE (RK PHARMA) APPROVAL= AP YEAR= 2015
NDA 205618 (pdf not found) INN (PALIPERIDONE) PALIPERIDONE (SUN PHARM) APPROVAL= AP YEAR= 2018
NDA 204452 (pdf not found) INN (PALIPERIDONE) PALIPERIDONE (INVENTIA) APPROVAL= AP YEAR= 2019
NDA 204707 (pdf not found) INN (PALIPERIDONE) PALIPERIDONE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2019
NDA 212807 (pdf not found) INN (PALIPERIDONE) PALIPERIDONE (CSPC OUYI) APPROVAL= AP YEAR= 2020
NDA 208643 (pdf not found) INN (PALIPERIDONE) PALIPERIDONE (LUPIN LTD) APPROVAL= AP YEAR= 2022
NDA 216174 (pdf not found) INN (PALIPERIDONE) PALIPERIDONE (ASCENT PHARMS INC) APPROVAL= AP YEAR= 2023
NDA 217445 (pdf not found) INN (PALIPERIDONE) PALIPERIDONE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2024
NDA 218330 (pdf not found) INN (PALIPERIDONE) PALIPERIDONE (ALEMBIC) APPROVAL= AP YEAR= 2024
NDA 218514 (pdf not found) INN (PALIPERIDONE) PALIPERIDONE (AJANTA PHARMA LTD) APPROVAL= AP YEAR= 2024
NDA 205559 (pdf not found) INN (PALIPERIDONE) PALIPERIDONE (DR REDDYS) APPROVAL= AP YEAR= 2025