e-Drug3D

942

cas 201530-41-8

CLASS

IRON CHELATING AGENTS
BETA THALASSAEMIA (DRUG FOR RARE DISEASE IN EUROPE)

ROUTE (list)

ORAL

PK parameters

F 70 PERCENT
Tmax 2.75 HOUR
VD 14 LITER
Cl 0.8 LITER / HOUR (EQN)
PPB 99 PERCENT
t1/2 12 HOUR

MW 372.35
NB_atoms 28
XLogP 0.78
PSA 92.511
NB_HD 2
NB_HA 7
fsp3 0.00
Lipinski(0=no;1=yes) 1

FDA
NDA 021882 (label) INN (DEFERASIROX) EXJADE (NOVARTIS) APPROVAL= AP YEAR= 2005
NDA 206910 (label) INN (DEFERASIROX) JADENU (NOVARTIS PHARMS CORP) APPROVAL= AP YEAR= 2015
NDA 203560 (label) INN (DEFERASIROX) DEFERASIROX (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 2016
NDA 207968 (label) INN (DEFERASIROX) JADENU SPRINKLE (NOVARTIS) APPROVAL= AP YEAR= 2017
NDA 208697 (pdf not found) INN (DEFERASIROX) DEFERASIROX (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 2019
NDA 211383 (pdf not found) INN (DEFERASIROX) DEFERASIROX (ZYDUS PHARMS) APPROVAL= AP YEAR= 2019
NDA 209223 (pdf not found) INN (DEFERASIROX) DEFERASIROX (TEVA PHARMS USA) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 209782 (pdf not found) INN (DEFERASIROX) DEFERASIROX (SUN PHARM) APPROVAL= AP YEAR= 2019
NDA 209878 (pdf not found) INN (DEFERASIROX) DEFERASIROX (MSN) APPROVAL= AP YEAR= 2019
NDA 210060 (pdf not found) INN (DEFERASIROX) DEFERASIROX (ALEMBIC) APPROVAL= AP YEAR= 2019
NDA 210519 (pdf not found) INN (DEFERASIROX) DEFERASIROX (ALKEM LABS LTD) APPROVAL= AP YEAR= 2019
NDA 210727 (pdf not found) INN (DEFERASIROX) DEFERASIROX (STEVENS J) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 210920 (pdf not found) INN (DEFERASIROX) DEFERASIROX (BIONPHARMA) APPROVAL= AP YEAR= 2019
NDA 210945 (pdf not found) INN (DEFERASIROX) DEFERASIROX (MSN) APPROVAL= AP YEAR= 2019
NDA 211824 (pdf not found) INN (DEFERASIROX) DEFERASIROX (ALEMBIC) APPROVAL= AP YEAR= 2019
NDA 212995 (pdf not found) INN (DEFERASIROX) DEFERASIROX (PIRAMAL) APPROVAL= AP YEAR= 2019
NDA 208882 (pdf not found) INN (DEFERASIROX) DEFERASIROX (ZYDUS PHARMS) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 209433 (pdf not found) INN (DEFERASIROX) DEFERASIROX (GLENMARK SPECLT) APPROVAL= AP YEAR= 2020
NDA 210555 (pdf not found) INN (DEFERASIROX) DEFERASIROX (ALKEM LABS LTD) APPROVAL= AP YEAR= 2020
NDA 211641 (pdf not found) INN (DEFERASIROX) DEFERASIROX (SUN PHARM) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 211852 (pdf not found) INN (DEFERASIROX) DEFERASIROX (CIPLA) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 213374 (pdf not found) INN (DEFERASIROX) DEFERASIROX (ALKEM LABS LTD) APPROVAL= AP YEAR= 2020
NDA 212669 (pdf not found) INN (DEFERASIROX) DEFERASIROX (CHARTWELL RX) APPROVAL= AP YEAR= 2021
NDA 214194 (pdf not found) INN (DEFERASIROX) DEFERASIROX (AMNEAL) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 214341 (pdf not found) INN (DEFERASIROX) DEFERASIROX (ANNORA PHARMA) APPROVAL= AP YEAR= 2021
NDA 214559 (pdf not found) INN (DEFERASIROX) DEFERASIROX (AUCTA) APPROVAL= AP YEAR= 2021
NDA 214650 (pdf not found) INN (DEFERASIROX) DEFERASIROX (MSN) APPROVAL= AP YEAR= 2021
NDA 214180 (pdf not found) INN (DEFERASIROX) DEFERASIROX (TEVA PHARMS USA) APPROVAL= AP YEAR= 2021
NDA 215026 (pdf not found) INN (DEFERASIROX) DEFERASIROX (CIPLA) APPROVAL= AP YEAR= 2022
NDA 207124 (pdf not found) INN (DEFERASIROX) DEFERASIROX (TEVA PHARMS USA) APPROVAL= AP YEAR= 2022
NDA 216229 (pdf not found) INN (DEFERASIROX) DEFERASIROX (ANNORA PHARMA) APPROVAL= AP YEAR= 2022
NDA 214474 (pdf not found) INN (DEFERASIROX) DEFERASIROX (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2023
NDA 209426 (pdf not found) INN (DEFERASIROX) DEFERASIROX (TORRENT) APPROVAL= AP YEAR= 2024 DISCONTINUED
NDA 206585 (pdf not found) INN (DEFERASIROX) DEFERASIROX (NORVIUM BIOSCIENCE) APPROVAL= AP YEAR= 2024 DISCONTINUED
NDA 211395 (pdf not found) INN (DEFERASIROX) DEFERASIROX (NORVIUM BIOSCIENCE) APPROVAL= AP YEAR= 2024
NDA 213146 (pdf not found) INN (DEFERASIROX) DEFERASIROX (NORVIUM BIOSCIENCE) APPROVAL= AP YEAR= 2024 DISCONTINUED
NDA 211660 (pdf not found) INN (DEFERASIROX) DEFERASIROX (JUBILANT GENERICS) APPROVAL= AP YEAR= 2025