e-Drug3D

940

cas 121032-29-9

CLASS

ANTINEOPLASTIC
PRODRUG
TREATMENT OF PATIENTS WITH T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA AND T-CELL LYMPHOBLASTIC LYMPHOMA

ROUTE (list)

INTRAVENOUS

PK parameters

VD 318.5 LITER
Cl 315 LITER / HOUR
PPB 25 PERCENT
t1/2 0.3 HOUR

MW 297.28
NB_atoms 21
XLogP -1.97
PSA 142.218
NB_HD 5
NB_HA 10
fsp3 0.55
Lipinski(0=no;1=yes) 0

FDA
NDA 021877 (label) INN (NELARABINE) ARRANON (SANDOZ) APPROVAL= AP YEAR= 2005
NDA 215037 (pdf not found) INN (NELARABINE) NELARABINE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2021
NDA 216934 (pdf not found) INN (NELARABINE) NELARABINE (DR REDDYS) APPROVAL= AP YEAR= 2022
NDA 214809 (pdf not found) INN (NELARABINE) NELARABINE (SHORLA) APPROVAL= AP YEAR= 2023
NDA 215057 (pdf not found) INN (NELARABINE) NELARABINE (NEXUS) APPROVAL= AP YEAR= 2023
NDA 216038 (pdf not found) INN (NELARABINE) NELARABINE (MEITHEAL) APPROVAL= AP YEAR= 2023
NDA 216346 (pdf not found) INN (NELARABINE) NELARABINE (AMNEAL) APPROVAL= AP YEAR= 2023
NDA 212605 (pdf not found) INN (NELARABINE) NELARABINE (GLAND) APPROVAL= AP YEAR= 2024
NDA 216510 (pdf not found) INN (NELARABINE) NELARABINE (XGEN PHARMS) APPROVAL= AP YEAR= 2024
NDA 216948 (pdf not found) INN (NELARABINE) NELARABINE (MSN) APPROVAL= AP YEAR= 2024
NDA 218554 (pdf not found) INN (NELARABINE) NELARABINE (ALEMBIC) APPROVAL= AP YEAR= 2024