e-Drug3D

936

cas 142217-69-4

CLASS

ANTIINFECTIVES
ANTIVIRAL
ANTI HEPATITIS B
GUANOSINE NUCLEOSIDE ANALOG

ROUTE (list)

ORAL

PK parameters

F 100 PERCENT
Tmax 1 HOUR
VD 5129 LITER
Cl 23 LITER / HOUR (RENAL CLEARANCE)
PPB 13 PERCENT
t1/2 138.5 HOUR

MW 277.29
NB_atoms 20
XLogP -0.83
PSA 121.244
NB_HD 5
NB_HA 8
fsp3 0.42
Lipinski(0=no;1=yes) 1

FDA
NDA 021797 (label) INN (ENTECAVIR) BARACLUDE (BRISTOL MYERS SQUIBB) APPROVAL= AP YEAR= 2005
NDA 021798 (label) INN (ENTECAVIR) BARACLUDE (BRISTOL MYERS SQUIBB) APPROVAL= AP YEAR= 2005
NDA 202122 (pdf not found) INN (ENTECAVIR) ENTECAVIR (TEVA PHARMS USA) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 205740 (pdf not found) INN (ENTECAVIR) ENTECAVIR (HETERO LABS LTD V) APPROVAL= AP YEAR= 2015
NDA 206217 (pdf not found) INN (ENTECAVIR) ENTECAVIR (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2015
NDA 206652 (pdf not found) INN (ENTECAVIR) ENTECAVIR (AMNEAL PHARMS) APPROVAL= AP YEAR= 2015
NDA 206294 (pdf not found) INN (ENTECAVIR) ENTECAVIR (CHARTWELL RX) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 206872 (pdf not found) INN (ENTECAVIR) ENTECAVIR (CIPLA) APPROVAL= AP YEAR= 2016
NDA 206672 (pdf not found) INN (ENTECAVIR) ENTECAVIR (CHARTWELL RX) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 206745 (pdf not found) INN (ENTECAVIR) ENTECAVIR (ZYDUS PHARMS) APPROVAL= AP YEAR= 2017
NDA 205824 (pdf not found) INN (ENTECAVIR) ENTECAVIR (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 208782 (pdf not found) INN (ENTECAVIR) ENTECAVIR (PRINSTON INC) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 208721 (pdf not found) INN (ENTECAVIR) ENTECAVIR (BRECKENRIDGE) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 206226 (pdf not found) INN (ENTECAVIR) ENTECAVIR (RISING) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 212126 (pdf not found) INN (ENTECAVIR) ENTECAVIR (BRIGHTGENE) APPROVAL= AP YEAR= 2019
NDA 212201 (pdf not found) INN (ENTECAVIR) ENTECAVIR (YAOPHARMA CO LTD) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 211978 (pdf not found) INN (ENTECAVIR) ENTECAVIR (SUNSHINE) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 212106 (pdf not found) INN (ENTECAVIR) ENTECAVIR (SWISS PHARM) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 208195 (pdf not found) INN (ENTECAVIR) ENTECAVIR (YUNG SHIN PHARM) APPROVAL= AP YEAR= 2021
NDA 216857 (pdf not found) INN (ENTECAVIR) ENTECAVIR (CONBA USA) APPROVAL= AP YEAR= 2024