e-Drug3D

934

cas 2353-33-5

CLASS

ANTINEOPLASTIC
ANTIMETABOLITES
TERATOGENS
TREATMENT OF MYELODYSPLASTIC SYNDROMES (MDS)
INDUCE HYPOMETHYLATION OF DNA

ROUTE (list)

INTRAVENOUS ORAL

PK parameters

VD 299 LITER (65 KILOGRAM)
Cl 130 LITER / HOUR
PPB 0 PERCENT
t1/2 0.54 HOUR

MW 228.22
NB_atoms 16
XLogP -2.14
PSA 118.789
NB_HD 4
NB_HA 8
fsp3 0.62
Lipinski(0=no;1=yes) 1

FDA
NDA 021790 (label) INN (DECITABINE) DACOGEN (OTSUKA) APPROVAL= AP YEAR= 2006 NEWMOLECULARENTITY DISCONTINUED
NDA 203131 (pdf not found) INN (DECITABINE) DECITABINE (DR REDDYS) APPROVAL= AP YEAR= 2013
NDA 202969 (pdf not found) INN (DECITABINE) DECITABINE (SANDOZ) APPROVAL= AP YEAR= 2014
NDA 205582 (label) INN (DECITABINE) DECITABINE (SUN PHARM) APPROVAL= AP YEAR= 2014
NDA 203475 (pdf not found) INN (DECITABINE) DECITABINE (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2017
NDA 204607 (pdf not found) INN (DECITABINE) DECITABINE (PHARMASCIENCE INC) APPROVAL= AP YEAR= 2017
NDA 206033 (pdf not found) INN (DECITABINE) DECITABINE (CHEMI SPA) APPROVAL= AP YEAR= 2017
NDA 208601 (pdf not found) INN (DECITABINE) DECITABINE (CIPLA) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 207100 (pdf not found) INN (DECITABINE) DECITABINE (SAGENT PHARMS INC) APPROVAL= AP YEAR= 2018
NDA 210756 (pdf not found) INN (DECITABINE) DECITABINE (LUPIN LTD) APPROVAL= AP YEAR= 2018
NDA 209056 (pdf not found) INN (DECITABINE) DECITABINE (WOCKHARDT BIO AG) APPROVAL= AP YEAR= 2019
NDA 210984 (pdf not found) INN (DECITABINE) DECITABINE (NOVAST LABS) APPROVAL= AP YEAR= 2019
NDA 212265 (pdf not found) INN (DECITABINE) DECITABINE (MSN) APPROVAL= AP YEAR= 2019
NDA 212576 (label) INN (CEDAZURIDINE ; DECITABINE) INQOVI (TAIHO ONCOLOGY) APPROVAL= AP YEAR= 2020
NDA 205539 (pdf not found) INN (DECITABINE) DECITABINE (GLAND) APPROVAL= AP YEAR= 2020
NDA 212117 (pdf not found) INN (DECITABINE) DECITABINE (NIVAGEN PHARMS INC) APPROVAL= AP YEAR= 2020
NDA 212826 (pdf not found) INN (DECITABINE) DECITABINE (QILU PHARM HAINAN) APPROVAL= AP YEAR= 2021
NDA 212959 (pdf not found) INN (DECITABINE) DECITABINE (MEITHEAL) APPROVAL= AP YEAR= 2021
NDA 214486 (pdf not found) INN (DECITABINE) DECITABINE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2021
NDA 214569 (pdf not found) INN (DECITABINE) DECITABINE (EUGIA PHARMA) APPROVAL= AP YEAR= 2021
NDA 213472 (pdf not found) INN (DECITABINE) DECITABINE (JIANGSU HANSOH PHARM) APPROVAL= AP YEAR= 2022
NDA 215355 (pdf not found) INN (DECITABINE) DECITABINE (HETERO LABS LTD VI) APPROVAL= AP YEAR= 2024