e-Drug3D

922

ANIDULAFUNGIN

INN
ANIDULAFUNGIN

cas 166663-25-8

CLASS

ANTIINFECTIVES
ANTIFUNGAL
ANTIBIOTICS

ROUTE (list)

INTRAVENOUS INJECTION

ATC code

J02AX06

PK parameters

VD 40 LITER
Cl 0.78 LITER / HOUR
PPB 99 PERCENT
t1/2 50.3 HOUR

Solubility

PRACTICALLY INSOLUBLE IN WATER

Target

TARGET BETA-1,3-GLUCAN SYNTHASE

DrugCentral

Beta-1,3-glucan synthase catalytic subunit 1 UNIPROT O13428 GSC1

Download SDF file

Echinocandin B, 1-[(4R,5R)-4,5-dihydroxy-N2-[[4''-(pentyloxy)[1,1':4',1''-terphenyl]-4-yl]carbonyl]-L-ornithine]-

Formula:
C58H73N7O17

Calculated chemical properties:

MW 1140.23
NB_atoms 82
XLogP -0.93
PSA 332.334
NB_HD 14
NB_HA 24
fsp3 0.47
Lipinski(0=no;1=yes) 0

FDA
NDA 021632 (pdf not found) INN (ANIDULAFUNGIN) ERAXIS (VICURON HOLDINGS) APPROVAL= AP YEAR= 2006
NDA 021948 (pdf not found) INN (ANIDULAFUNGIN) ERAXIS (PFIZER) APPROVAL= AP YEAR= 2006 NEWAPPLICATION