e-Drug3D
912
MICAFUNGIN
INN
MICAFUNGIN
cas 235114-32-6
CLASS
ANTIINFECTIVES
ANTIFUNGALS
MEMBER OF THE ECHINOCANDIN CLASS OF ANTIFUNGAL AGENTS
ROUTE (list)
INTRAVENOUS INJECTION
ATC code
J02AX05
PK parameters
VD 25.35 LITER (65 KILOGRAM)
Cl 1.16 LITER / HOUR (65 KILOGRAM)
PPB 99 PERCENT
t1/2 13.4 HOUR
Solubility
FREELY SOLUBLE IN WATER
TARGET BETA-1,3-GLUCAN SYNTHASE
Beta-1,3-glucan synthase catalytic subunit 1 UNIPROT O13428 GSC1
Formula:
C56H71N9O23S
Calculated chemical properties:
MW 1270.29
NB_atoms 89
XLogP -3.90
PSA 452.725
NB_HD 17
NB_HA 32
fsp3 0.48
Lipinski(0=no;1=yes) 0
NB_atoms 89
XLogP -3.90
PSA 452.725
NB_HD 17
NB_HA 32
fsp3 0.48
Lipinski(0=no;1=yes) 0
FDA
NDA 021506 (label) INN (MICAFUNGIN SODIUM) MYCAMINE (ASTELLAS) APPROVAL= TA YEAR= 2005
NDA 021754 (label) INN (MICAFUNGIN SODIUM) MYCAMINE (FUJISAWA HLTHCARE) APPROVAL= AP YEAR= 2005 NEWAPPLICATION
NDA 207344 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2019
NDA 208366 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (APOTEX) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 212125 (label) INN (MICAFUNGIN SODIUM) MICAFUNGIN (TEVA PHARMS USA INC) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 213363 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (JIANGSU HANSOH PHARM) APPROVAL= AP YEAR= 2021
NDA 211713 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (XELLIA PHARMS APS) APPROVAL= AP YEAR= 2021
NDA 212156 (label) INN (MICAFUNGIN SODIUM) MICAFUNGIN (PH HEALTH) APPROVAL= AP YEAR= 2021
NDA 213261 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (HIKMA) APPROVAL= AP YEAR= 2021
NDA 215241 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (ZYDUS PHARMS) APPROVAL= AP YEAR= 2022
NDA 215381 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (MEITHEAL) APPROVAL= AP YEAR= 2022
NDA 216142 (label) INN (MICAFUNGIN SODIUM) MICAFUNGIN IN SODIUM CHLORIDE 0.9% (BAXTER HLTHCARE CORP) APPROVAL= AP YEAR= 2023
NDA 216438 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (BIOCON PHARMA) APPROVAL= AP YEAR= 2024
NDA 219273 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (QILU PHARM HAINAN) APPROVAL= AP YEAR= 2025
NDA 021506 (label) INN (MICAFUNGIN SODIUM) MYCAMINE (ASTELLAS) APPROVAL= TA YEAR= 2005
NDA 021754 (label) INN (MICAFUNGIN SODIUM) MYCAMINE (FUJISAWA HLTHCARE) APPROVAL= AP YEAR= 2005 NEWAPPLICATION
NDA 207344 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2019
NDA 208366 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (APOTEX) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 212125 (label) INN (MICAFUNGIN SODIUM) MICAFUNGIN (TEVA PHARMS USA INC) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 213363 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (JIANGSU HANSOH PHARM) APPROVAL= AP YEAR= 2021
NDA 211713 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (XELLIA PHARMS APS) APPROVAL= AP YEAR= 2021
NDA 212156 (label) INN (MICAFUNGIN SODIUM) MICAFUNGIN (PH HEALTH) APPROVAL= AP YEAR= 2021
NDA 213261 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (HIKMA) APPROVAL= AP YEAR= 2021
NDA 215241 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (ZYDUS PHARMS) APPROVAL= AP YEAR= 2022
NDA 215381 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (MEITHEAL) APPROVAL= AP YEAR= 2022
NDA 216142 (label) INN (MICAFUNGIN SODIUM) MICAFUNGIN IN SODIUM CHLORIDE 0.9% (BAXTER HLTHCARE CORP) APPROVAL= AP YEAR= 2023
NDA 216438 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (BIOCON PHARMA) APPROVAL= AP YEAR= 2024
NDA 219273 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (QILU PHARM HAINAN) APPROVAL= AP YEAR= 2025