e-Drug3D

896

cas 224785-90-4

CLASS

GENITO
TREATMENT OF ERECTILE DYSFUNCTION
CYCLIC GUANOSINE MONOPHOSPHATE (CGMP)-SPECIFIC PHOSPHODIESTERASE TYPE 5 (PDE5) INHIBITOR
ANTI-IMPOTENCE AGENTS
VASOCONSTRICTOR AGENTS

ROUTE (list)

ORAL

PK parameters

F 15 PERCENT
Tmax 1 HOUR
VD 208 LITER
Cl 56 LITER / HOUR
PPB 95 PERCENT
t1/2 4.5 HOUR

MW 488.62
NB_atoms 34
XLogP 2.07
PSA 102.495
NB_HD 1
NB_HA 10
fsp3 0.52
Lipinski(0=no;1=yes) 1

FDA
NDA 021400 (label) INN (VARDENAFIL HYDROCHLORIDE) LEVITRA (BAYER HLTHCARE) APPROVAL= AP YEAR= 2003 NEWMOLECULARENTITY DISCONTINUED
NDA 200179 (label) INN (VARDENAFIL HYDROCHLORIDE) STAXYN (BAYER HLTHCARE) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 091347 (pdf not found) INN (VARDENAFIL HYDROCHLORIDE) VARDENAFIL HYDROCHLORIDE (TEVA PHARMS) APPROVAL= AP YEAR= 2012
NDA 204786 (pdf not found) INN (VARDENAFIL HYDROCHLORIDE) VARDENAFIL HYDROCHLORIDE (PAR PHARM INC) APPROVAL= TA YEAR= 2016
NDA 203689 (pdf not found) INN (VARDENAFIL HYDROCHLORIDE) VARDENAFIL HYDROCHLORIDE (WATSON LABS TEVA) APPROVAL= TA YEAR= 2017
NDA 208324 (pdf not found) INN (VARDENAFIL HYDROCHLORIDE) VARDENAFIL HYDROCHLORIDE (ALEMBIC) APPROVAL= AP YEAR= 2018
NDA 208960 (pdf not found) INN (VARDENAFIL HYDROCHLORIDE) VARDENAFIL HYDROCHLORIDE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2018
NDA 209057 (pdf not found) INN (VARDENAFIL HYDROCHLORIDE) VARDENAFIL HYDROCHLORIDE (CROSSMEDIKA SA) APPROVAL= AP YEAR= 2018
NDA 210738 (pdf not found) INN (VARDENAFIL HYDROCHLORIDE) VARDENAFIL HYDROCHLORIDE (STEVENS J) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 204632 (pdf not found) INN (VARDENAFIL HYDROCHLORIDE) VARDENAFIL HYDROCHLORIDE (MACLEODS PHARMS LTD) APPROVAL= AP YEAR= 2019
NDA 205988 (pdf not found) INN (VARDENAFIL HYDROCHLORIDE) VARDENAFIL HYDROCHLORIDE (MACLEODS PHARMS LTD) APPROVAL= AP YEAR= 2020
NDA 214031 (pdf not found) INN (VARDENAFIL HYDROCHLORIDE) VARDENAFIL HYDROCHLORIDE (ALEMBIC) APPROVAL= AP YEAR= 2020