e-Drug3D

887

cas 129453-61-8

CLASS

ANTINEOPLASTIC
BREAST CANCER (THERAPEUTIC)
ANTIESTROGENIC
ESTROGEN ANTAGONISTS
TREATMENT OF HORMONE RECEPTOR POSITIVE METASTATIC BREAST CANCER

ROUTE (list)

INTRAMUSCULAR

PK parameters

VD 260 LITER (65 KILOGRAM)
Cl 41.4 LITER / HOUR
PPB 99 PERCENT
t1/2 960 HOUR

TARGET ESTROGEN RECEPTOR

PDB
4J03 (CRYSTAL STRUCTURE OF HUMAN SOLUBLE EPOXIDE HYDROLASE COMPLEXED WITH FULVESTRANT)

Ligand code = FVS (link to the list of PDB complexes)

Download experimental 3D coordinates of FVS with added hydrogens

MW 606.77
NB_atoms 41
XLogP 8.68
PSA 59.406
NB_HD 2
NB_HA 3
fsp3 0.81
Lipinski(0=no;1=yes) 0

FDA
NDA 021344 (pdf not found) INN (FULVESTRANT) FASLODEX (ASTRAZENECA) APPROVAL= AP YEAR= 2002
NDA 205935 (pdf not found) INN (FULVESTRANT) FULVESTRANT (SANDOZ) APPROVAL= AP YEAR= 2019
NDA 207754 (pdf not found) INN (FULVESTRANT) FULVESTRANT (GLENMARK PHARMS INC) APPROVAL= AP YEAR= 2019
NDA 210044 (pdf not found) INN (FULVESTRANT) FULVESTRANT (AMNEAL) APPROVAL= AP YEAR= 2019
NDA 205871 (pdf not found) INN (FULVESTRANT) FULVESTRANT (SAGENT PHARMS INC) APPROVAL= AP YEAR= 2019
NDA 208811 (pdf not found) INN (FULVESTRANT) FULVESTRANT (EUGIA PHARMA) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 209714 (pdf not found) INN (FULVESTRANT) FULVESTRANT (HBT LABS INC) APPROVAL= AP YEAR= 2019
NDA 210063 (pdf not found) INN (FULVESTRANT) FULVESTRANT (AVYXA HOLDINGS) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 210326 (pdf not found) INN (FULVESTRANT) FULVESTRANT (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2019
NDA 211422 (pdf not found) INN (FULVESTRANT) FULVESTRANT (CHIA TAI TIANQING) APPROVAL= AP YEAR= 2020
NDA 209246 (pdf not found) INN (FULVESTRANT) FULVESTRANT (DR REDDYS) APPROVAL= AP YEAR= 2020
NDA 211689 (pdf not found) INN (FULVESTRANT) FULVESTRANT (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2020
NDA 211730 (pdf not found) INN (FULVESTRANT) FULVESTRANT (APOTEX) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 213553 (pdf not found) INN (FULVESTRANT) FULVESTRANT (XIROMED) APPROVAL= AP YEAR= 2021
NDA 215234 (pdf not found) INN (FULVESTRANT) FULVESTRANT (ZYDUS PHARMS) APPROVAL= AP YEAR= 2021
NDA 214682 (pdf not found) INN (FULVESTRANT) FULVESTRANT (JIANGSU HANSOH PHARM) APPROVAL= AP YEAR= 2022
NDA 215077 (pdf not found) INN (FULVESTRANT) FULVESTRANT (ALEMBIC) APPROVAL= AP YEAR= 2022
NDA 215169 (pdf not found) INN (FULVESTRANT) FULVESTRANT (EUGIA PHARMA) APPROVAL= AP YEAR= 2023