e-Drug3D

859

cas 81403-80-7

CLASS

GENITO
ANTIHYPERTENSIVE
ALPHA ADRENERGIC ANTAGONISTS
TREATMENT OF BENIGN PROSTATIC HYPERPLASIA

ROUTE (list)

ORAL

PK parameters

F 49 PERCENT
Tmax 8 HOUR
VD 208 LITER (65 KILOGRAM)
Cl 23 LITER / HOUR (65 KILOGRAM)
PPB 86 PERCENT
t1/2 10 HOUR

MW 389.46
NB_atoms 28
XLogP 1.35
PSA 107.297
NB_HD 3
NB_HA 9
fsp3 0.53
Lipinski(0=no;1=yes) 1

FDA
NDA 021287 (label) INN (ALFUZOSIN HYDROCHLORIDE) UROXATRAL (ADVANZ PHARMA) APPROVAL= AP YEAR= 2003
NDA 079013 (pdf not found) INN (ALFUZOSIN HYDROCHLORIDE) ALFUZOSIN HYDROCHLORIDE (APOTEX INC) APPROVAL= AP YEAR= 2011
NDA 079014 (pdf not found) INN (ALFUZOSIN HYDROCHLORIDE) ALFUZOSIN HYDROCHLORIDE (PHARMOBEDIENT) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 079054 (pdf not found) INN (ALFUZOSIN HYDROCHLORIDE) ALFUZOSIN HYDROCHLORIDE (TORRENT PHARMS) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 079056 (pdf not found) INN (ALFUZOSIN HYDROCHLORIDE) ALFUZOSIN HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 079057 (pdf not found) INN (ALFUZOSIN HYDROCHLORIDE) ALFUZOSIN HYDROCHLORIDE (SUN PHARM) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 079060 (pdf not found) INN (ALFUZOSIN HYDROCHLORIDE) ALFUZOSIN HYDROCHLORIDE (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2012
NDA 090221 (pdf not found) INN (ALFUZOSIN HYDROCHLORIDE) ALFUZOSIN HYDROCHLORIDE (WOCKHARDT BIO AG) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 090284 (pdf not found) INN (ALFUZOSIN HYDROCHLORIDE) ALFUZOSIN HYDROCHLORIDE (INVAGEN PHARMS) APPROVAL= AP YEAR= 2012
NDA 203192 (pdf not found) INN (ALFUZOSIN HYDROCHLORIDE) ALFUZOSIN HYDROCHLORIDE (UNICHEM) APPROVAL= AP YEAR= 2016