e-Drug3D

857

HYDROQUINONE

INN
HYDROQUINONE

cas 123-31-9

CLASS

DERMATOLOGICAL
ANTIOXIDANT
DEPIGMENTOR
MAY INTERRUPT ONE OR MORE STEPS IN THE TYROSINE-TYROSINASE PATHWAY OF MELANIN SYNTHESIS

ROUTE (list)

TOPICAL

NATURAL MOLECULE (link)

ATC code

D11AX11

PK parameters

Solubility

FREELY SOLUBLE IN WATER

Target

PDB
4QOP (STRUCTURE OF BACILLUS PUMILUS CATALASE WITH HYDROQUINONE BOUND.)

Download experimental 3D coordinates of HQE with added hydrogens

Carbonic anhydrase 14 UNIPROT Q9ULX7 CA14

Download SDF file

1,4-Benzenediol

Formula:
C6H6O2

Calculated chemical properties:

MW 110.11
NB_atoms 8
XLogP 1.10
PSA 42.88
NB_HD 2
NB_HA 2
fsp3 0.00
Lipinski(0=no;1=yes) 1

FDA
NDA 021112 (pdf not found) INN (FLUOCINOLONE ACETONIDE ; HYDROQUINONE ; TRETINOIN) TRI-LUMA (GALDERMA LABS LP) APPROVAL= AP YEAR= 2002