e-Drug3D

845

cas 113775-47-6

CLASS

NERVOUS SYSTEM
ADRENERGIC ALPHA AGONISTS
HYPNOTICS AND SEDATIVES

ROUTE (list)

INJECTION INTRAVENOUS BUCCAL SUBLINGUAL

PK parameters

VD 118 LITER
Cl 39 LITER / HOUR (72 KILOGRAM)
PPB 94 PERCENT
t1/2 2 HOUR

MW 200.28
NB_atoms 15
XLogP 3.18
PSA 25.403
NB_HD 1
NB_HA 2
fsp3 0.31
Lipinski(0=no;1=yes) 1

FDA
NDA 021038 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) PRECEDEX (HOSPIRA) APPROVAL= AP YEAR= 1999 NEWMOLECULARENTITY
NDA 202585 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2014
NDA 202881 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (MYLAN INSTITUTIONAL) APPROVAL= AP YEAR= 2014
NDA 203972 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (PH HEALTH) APPROVAL= AP YEAR= 2014
NDA 202126 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (GLAND) APPROVAL= AP YEAR= 2015
NDA 201072 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2015
NDA 206628 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (HQ SPCLT PHARMA) APPROVAL= AP YEAR= 2015
NDA 091465 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (SANDOZ) APPROVAL= AP YEAR= 2016
NDA 204023 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2016
NDA 205867 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (EUGIA PHARMA) APPROVAL= AP YEAR= 2016
NDA 204686 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (ACTAVIS INC) APPROVAL= AP YEAR= 2016
NDA 203773 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (AM REGENT) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 205046 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 2017
NDA 205272 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2017
NDA 209065 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (HENGRUI PHARMA) APPROVAL= AP YEAR= 2017
NDA 206798 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2018
NDA 208129 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2018
NDA 208532 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (BAXTER HLTHCARE CORP) APPROVAL= AP YEAR= 2018
NDA 204843 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (MEITHEAL) APPROVAL= AP YEAR= 2019
NDA 212791 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (WILSHIRE PHARMS INC) APPROVAL= AP YEAR= 2019
NDA 207551 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (AMNEAL PHARMS CO) APPROVAL= AP YEAR= 2020
NDA 206407 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 2020
NDA 209307 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (GLAND) APPROVAL= AP YEAR= 2020
NDA 208266 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (PH HEALTH) APPROVAL= AP YEAR= 2020
NDA 210321 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (EUGIA PHARMA) APPROVAL= AP YEAR= 2020
NDA 212571 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (MYLAN LABS LTD) APPROVAL= AP YEAR= 2020
NDA 212857 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (TAGI) APPROVAL= AP YEAR= 2020
NDA 214794 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (PIRAMAL CRITICAL) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 215390 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) IGALMI (BIOXCEL) APPROVAL= AP YEAR= 2022
NDA 216604 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (AMNEAL) APPROVAL= AP YEAR= 2023
NDA 217308 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (MILLA PHARMS) APPROVAL= AP YEAR= 2023
NDA 218112 (pdf not found) INN (DEXMEDETOMIDINE HYDROCHLORIDE) DEXMEDETOMIDINE HYDROCHLORIDE (SOMERSET) APPROVAL= AP YEAR= 2024