e-Drug3D

836

cas 169590-42-5

CLASS

MUSCULO-SKELETAL SYSTEM
ANTIARTHRITIC
ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL NSAID
CYCLOOXYGENASE INHIBITORS

ROUTE (list)

ORAL

PK parameters

Tmax 3 HOUR
VD 429 LITER
Cl 27.7 LITER / HOUR
PPB 97 PERCENT
t1/2 11.2 HOUR

TARGET PROSTAGLANDIN G/H SYNTHASE 2

PDB
3KK6 (CRYSTAL STRUCTURE OF CYCLOOXYGENASE-1 IN COMPLEX WITH CELECOXIB)

Ligand code = CEL (link to the list of PDB complexes)

Download experimental 3D coordinates of CEL with added hydrogens

MW 381.38
NB_atoms 26
XLogP 3.51
PSA 75.497
NB_HD 2
NB_HA 5
fsp3 0.12
Lipinski(0=no;1=yes) 1

FDA
NDA 020998 (pdf not found) INN (CELECOXIB) CELEBREX (UPJOHN) APPROVAL= AP YEAR= 1998
NDA 021156 (pdf not found) INN (CELECOXIB) CELEBREX (GD SEARLE LLC) APPROVAL= AP YEAR= 1999
NDA 078857 (pdf not found) INN (CELECOXIB) CELECOXIB (PHARMOBEDIENT) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 076898 (pdf not found) INN (CELECOXIB) CELECOXIB (TEVA) APPROVAL= AP YEAR= 2014
NDA 202240 (pdf not found) INN (CELECOXIB) CELECOXIB (LUPIN LTD) APPROVAL= AP YEAR= 2014
NDA 200562 (pdf not found) INN (CELECOXIB) CELECOXIB (WATSON LABS INC) APPROVAL= AP YEAR= 2015
NDA 204197 (pdf not found) INN (CELECOXIB) CELECOXIB (APOTEX) APPROVAL= AP YEAR= 2015
NDA 204519 (pdf not found) INN (CELECOXIB) CELECOXIB (ALEMBIC) APPROVAL= AP YEAR= 2015
NDA 207446 (pdf not found) INN (CELECOXIB) CELECOXIB (CIPLA) APPROVAL= AP YEAR= 2015
NDA 207677 (pdf not found) INN (CELECOXIB) CELECOXIB (TORRENT) APPROVAL= AP YEAR= 2015
NDA 204590 (pdf not found) INN (CELECOXIB) CELECOXIB (MACLEODS PHARMS LTD) APPROVAL= AP YEAR= 2016
NDA 206827 (pdf not found) INN (CELECOXIB) CELECOXIB (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2016
NDA 207061 (pdf not found) INN (CELECOXIB) CELECOXIB (JUBILANT GENERICS) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 204776 (pdf not found) INN (CELECOXIB) CELECOXIB (MICRO LABS) APPROVAL= AP YEAR= 2018
NDA 208833 (pdf not found) INN (CELECOXIB) CELECOXIB (AMNEAL PHARMS) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 210045 (pdf not found) INN (AMLODIPINE BESYLATE ; CELECOXIB) CONSENSI (PURPLE BIOTECH) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 210071 (pdf not found) INN (CELECOXIB) CELECOXIB (CSPC OUYI) APPROVAL= AP YEAR= 2018
NDA 208701 (pdf not found) INN (CELECOXIB) CELECOXIB (CADILA PHARMS LTD) APPROVAL= AP YEAR= 2019
NDA 208856 (pdf not found) INN (CELECOXIB) CELECOXIB (QINGDAO BAHEAL PHARM) APPROVAL= AP YEAR= 2019
NDA 210628 (pdf not found) INN (CELECOXIB) CELECOXIB (UMEDICA) APPROVAL= AP YEAR= 2019
NDA 207872 (pdf not found) INN (CELECOXIB) CELECOXIB (TIANJIN TIANYAO) APPROVAL= AP YEAR= 2020
NDA 211412 (pdf not found) INN (CELECOXIB) CELECOXIB (YILING) APPROVAL= AP YEAR= 2020
NDA 212157 (pdf not found) INN (CELECOXIB) ELYXYB (SCILEX PHARMS) APPROVAL= AP YEAR= 2020
NDA 213598 (pdf not found) INN (CELECOXIB) CELECOXIB (NANJING) APPROVAL= AP YEAR= 2020
NDA 205129 (pdf not found) INN (CELECOXIB) CELECOXIB (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 2020
NDA 212925 (pdf not found) INN (CELECOXIB) CELECOXIB (PANGEA) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 213301 (pdf not found) INN (CELECOXIB) CELECOXIB (UNICHEM) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 213426 (pdf not found) INN (CELECOXIB ; TRAMADOL HYDROCHLORIDE) SEGLENTIS (KOWA PHARMS) APPROVAL= AP YEAR= 2021
NDA 212564 (pdf not found) INN (CELECOXIB) CELECOXIB (YABAO PHARM) APPROVAL= AP YEAR= 2023 DISCONTINUED
NDA 205938 (pdf not found) INN (CELECOXIB) CELECOXIB (ZYDUS PHARMS) APPROVAL= AP YEAR= 2025
NDA 211759 (pdf not found) INN (CELECOXIB) VYSCOXA (CARWIN PHARM ASSOC) APPROVAL= AP YEAR= 2025
NDA 213127 (pdf not found) INN (CELECOXIB) CELECOXIB (STRIDES PHARMA) APPROVAL= AP YEAR= 2025 DISCONTINUED