e-Drug3D

834

cas 107233-08-9

CLASS

NERVOUS SYSTEM
MUSCARINIC AGONIST
CHOLINERGIC AGONIST
ANTI-ALZHEIMER'S DISEASE
PARASYMPATHOMIMETICS

ROUTE (list)

ORAL

PK parameters

Tmax 1.75 HOUR
VD 390 LITER (65 KILOGRAM)
Cl 54 LITER / HOUR (EQN)
PPB 20 PERCENT
t1/2 5 HOUR

MW 199.32
NB_atoms 13
XLogP 1.56
PSA 14.484
NB_HD 0
NB_HA 2
fsp3 1.00
Lipinski(0=no;1=yes) 1

FDA
NDA 020989 (pdf not found) INN (CEVIMELINE HYDROCHLORIDE) EVOXAC (COSETTE) APPROVAL= AP YEAR= 2000 NEWMOLECULARENTITY
NDA 091260 (pdf not found) INN (CEVIMELINE HYDROCHLORIDE) CEVIMELINE HYDROCHLORIDE (APOTEX INC) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 091591 (pdf not found) INN (CEVIMELINE HYDROCHLORIDE) CEVIMELINE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 2013
NDA 203775 (pdf not found) INN (CEVIMELINE HYDROCHLORIDE) CEVIMELINE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2014
NDA 204746 (pdf not found) INN (CEVIMELINE HYDROCHLORIDE) CEVIMELINE HYDROCHLORIDE (NOVEL LABS INC) APPROVAL= AP YEAR= 2016
NDA 215056 (pdf not found) INN (CEVIMELINE HYDROCHLORIDE) CEVIMELINE HYDROCHLORIDE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2023
NDA 216682 (pdf not found) INN (CEVIMELINE HYDROCHLORIDE) CEVIMELINE HYDROCHLORIDE (RUBICON RESEARCH) APPROVAL= AP YEAR= 2023
NDA 218290 (pdf not found) INN (CEVIMELINE HYDROCHLORIDE) CEVIMELINE HYDROCHLORIDE (BIONPHARMA) APPROVAL= AP YEAR= 2023
NDA 206808 (pdf not found) INN (CEVIMELINE HYDROCHLORIDE) CEVIMELINE HYDROCHLORIDE (MACLEODS PHARMS LTD) APPROVAL= AP YEAR= 2024