e-Drug3D

824

CHOLECALCIFEROL

INN
CHOLECALCIFEROL

cas 67-97-0

CLASS

METABOLISM
VITAMIN D3
ANTIARTHRITIC
ANTIHYPOCALCEMIC AGENTS
ANTIHYPOPARATHYROID AGENTS
BONE DENSITY CONSERVATION AGENTS
SECOSTEROL

ROUTE (list)

INTRAVENOUS ORAL

ATC code

M05BB03
A11CC05
A11CC55
M05BB09
M05BB07
M05BX53

PK parameters

Tmax 10.6 HOUR
t1/2 14 HOUR

Solubility

PRACTICALLY INSOLUBLE IN WATER

Target

TARGET VITAMIN D3-25-HYDROXYLASE (25-OHASE)

DrugCentral

Vitamin D3 receptor UNIPROT P11473 VDR

Download SDF file

(1S)-3-[2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol

Formula:
C27H44O

Calculated chemical properties:

MW 384.62
NB_atoms 28
XLogP 7.62
PSA 21.28
NB_HD 1
NB_HA 1
fsp3 0.78
Lipinski(0=no;1=yes) 0

FDA
NDA 021163 (pdf not found) INN (CHOLECALCIFEROL) INFUVITE ADULT (SANDOZ CANADA INC) APPROVAL= AP YEAR= 2000
NDA 021265 (pdf not found) INN (CHOLECALCIFEROL) INFUVITE PEDIATRIC (SANDOZ CANADA INC) APPROVAL= AP YEAR= 2001
NDA 021559 (pdf not found) INN (CHOLECALCIFEROL) INFUVITE ADULT (SANDOZ INC) APPROVAL= AP YEAR= 2003 OBSOLETE
NDA 021646 (pdf not found) INN (CHOLECALCIFEROL) INFUVITE PEDIATRIC PHARMACY BULK PACKAGE (SANDOZ INC) APPROVAL= AP YEAR= 2004 OBSOLETE
NDA 021762 (pdf not found) INN (ALENDRONATE SODIUM ; CHOLECALCIFEROL) FOSAMAX PLUS D (ORGANON LLC) APPROVAL= AP YEAR= 2005