e-Drug3D

822

cas 75706-12-6

CLASS

IMMUNOSUPPRESSANTS
IMMUNOMODULATIONG AGENT
PYRIMIDINE SYNTHESIS INHIBITOR
TREATMENT OF PATIENTS WITH RELAPSING FORMS OF MULTIPLE SCLEROSIS
ANTIINFLAMMATORY

ROUTE (list)

ORAL

PK parameters

MW 270.21
NB_atoms 19
XLogP 3.25
PSA 50.495
NB_HD 1
NB_HA 4
fsp3 0.17
Lipinski(0=no;1=yes) 1

FDA
NDA 020905 (pdf not found) INN (LEFLUNOMIDE) ARAVA (SANOFI AVENTIS US) APPROVAL= AP YEAR= 1998
NDA 077083 (pdf not found) INN (LEFLUNOMIDE) LEFLUNOMIDE (BARR) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077084 (pdf not found) INN (LEFLUNOMIDE) LEFLUNOMIDE (TEVA PHARMS) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077085 (pdf not found) INN (LEFLUNOMIDE) LEFLUNOMIDE (SANDOZ) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077086 (pdf not found) INN (LEFLUNOMIDE) LEFLUNOMIDE (HERITAGE) APPROVAL= AP YEAR= 2005
NDA 077087 (pdf not found) INN (LEFLUNOMIDE) LEFLUNOMIDE (FOSUN WANBANG) APPROVAL= AP YEAR= 2005
NDA 077090 (pdf not found) INN (LEFLUNOMIDE) LEFLUNOMIDE (APOTEX) APPROVAL= AP YEAR= 2005
NDA 091369 (pdf not found) INN (LEFLUNOMIDE) LEFLUNOMIDE (ALEMBIC PHARMS LTD) APPROVAL= AP YEAR= 2011
NDA 212308 (pdf not found) INN (LEFLUNOMIDE) LEFLUNOMIDE (ZYDUS LIFESCIENCES) APPROVAL= AP YEAR= 2019
NDA 212453 (pdf not found) INN (LEFLUNOMIDE) LEFLUNOMIDE (ABHAI LLC) APPROVAL= AP YEAR= 2019
NDA 211863 (pdf not found) INN (LEFLUNOMIDE) LEFLUNOMIDE (LUPIN LTD) APPROVAL= AP YEAR= 2020
NDA 213497 (pdf not found) INN (LEFLUNOMIDE) LEFLUNOMIDE (AET PHARMA) APPROVAL= AP YEAR= 2021
NDA 213652 (pdf not found) INN (LEFLUNOMIDE) LEFLUNOMIDE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2021