e-Drug3D

821

cas 154361-50-9

CLASS

ANTINEOPLASTIC
BREAST CANCER
COLORECTAL CANCER
COLON CANCER
ANTIMETABOLITES
NUCLEOSIDE METABOLIC INHIBITOR
METABOLIZED ENZYMATICALLY TO 5-FU

ROUTE (list)

ORAL

PK parameters

Tmax 1.5 HOUR
PPB 60 PERCENT
t1/2 0.75 HOUR

MW 359.36
NB_atoms 25
XLogP 0.76
PSA 112.707
NB_HD 3
NB_HA 9
fsp3 0.67
Lipinski(0=no;1=yes) 1

FDA
NDA 020896 (label) INN (CAPECITABINE) XELODA (CHEPLAPHARM) APPROVAL= AP YEAR= 1998
NDA 091649 (label) INN (CAPECITABINE) CAPECITABINE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2013
NDA 090943 (pdf not found) INN (CAPECITABINE) CAPECITABINE (RISING) APPROVAL= AP YEAR= 2014
NDA 202593 (pdf not found) INN (CAPECITABINE) CAPECITABINE (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2015
NDA 200483 (pdf not found) INN (CAPECITABINE) CAPECITABINE (HIKMA) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 207456 (pdf not found) INN (CAPECITABINE) CAPECITABINE (SHILPA) APPROVAL= AP YEAR= 2016
NDA 204741 (pdf not found) INN (CAPECITABINE) CAPECITABINE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 207652 (pdf not found) INN (CAPECITABINE) CAPECITABINE (ALKEM LABS LTD) APPROVAL= AP YEAR= 2017
NDA 210604 (pdf not found) INN (CAPECITABINE) CAPECITABINE (EUGIA PHARMA) APPROVAL= AP YEAR= 2018
NDA 209365 (pdf not found) INN (CAPECITABINE) CAPECITABINE (MSN) APPROVAL= AP YEAR= 2018
NDA 204668 (pdf not found) INN (CAPECITABINE) CAPECITABINE (SUN PHARM) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 211724 (pdf not found) INN (CAPECITABINE) CAPECITABINE (RELIANCE LIFE) APPROVAL= AP YEAR= 2020
NDA 204345 (pdf not found) INN (CAPECITABINE) CAPECITABINE (DR REDDYS) APPROVAL= AP YEAR= 2020
NDA 217237 (pdf not found) INN (CAPECITABINE) CAPECITABINE (TEYRO LABS) APPROVAL= AP YEAR= 2023
NDA 210203 (pdf not found) INN (CAPECITABINE) CAPECITABINE (HETERO LABS LTD V) APPROVAL= AP YEAR= 2024