e-Drug3D
82
cas 50-04-4
CLASS
METABOLISM
GLUCOCORTICOID
ANTIINFLAMMATORY
VASOCONSTRICTOR
REPLACEMENT THERAPY IN ADRENOCORTICAL DEFICIENCY STATES
PSORIATIC
ARTHRITIS RHEUMATOID ARTHRITIS
RAPIDLY HYDROLYZED IN CORTISONE
ROUTE (list)
INJECTION ORAL
PK parameters
Solubility
INSOLUBLE IN WATER
TARGET GLUCOCORTICOID RECEPTOR
Glucocorticoid receptor UNIPROT P04150 NR3C1
Formula:
C23H30O6
Calculated chemical properties:
MW 402.47
NB_atoms 29
XLogP 2.56
PSA 90.693
NB_HD 1
NB_HA 6
fsp3 0.74
Lipinski(0=no;1=yes) 1
NB_atoms 29
XLogP 2.56
PSA 90.693
NB_HD 1
NB_HA 6
fsp3 0.74
Lipinski(0=no;1=yes) 1
FDA
NDA 080333 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (VITARINE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080493 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080731 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (INWOOD LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080836 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (ELKINS SINN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 083147 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085736 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (HEATHER) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 007110 (pdf not found) INN (CORTISONE ACETATE) CORTONE (MERCK) APPROVAL= AP YEAR= 1950 NEWMOLECULARENTITY DISCONTINUED
NDA 007750 (pdf not found) INN (CORTISONE ACETATE) CORTONE (MERCK) APPROVAL= AP YEAR= 1950 DISCONTINUED
NDA 008126 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (PHARMACIA AND UPJOHN) APPROVAL= AP YEAR= 1951 DISCONTINUED
NDA 008284 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (PANRAY) APPROVAL= AP YEAR= 1952 DISCONTINUED
NDA 080630 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 080776 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (HIKMA INTL PHARMS) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 080341 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (WHITEWORTH TOWN PLSN) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 083471 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (BARR) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 083536 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 080694 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (CHARTWELL MOLECULAR) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 084246 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (EVERYLIFE) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 009458 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (IMPAX LABS) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085677 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (WATSON LABS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085884 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (WATSON LABS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 080333 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (VITARINE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080493 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (PUREPAC PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080731 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (INWOOD LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080836 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (ELKINS SINN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 083147 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085736 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (HEATHER) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 007110 (pdf not found) INN (CORTISONE ACETATE) CORTONE (MERCK) APPROVAL= AP YEAR= 1950 NEWMOLECULARENTITY DISCONTINUED
NDA 007750 (pdf not found) INN (CORTISONE ACETATE) CORTONE (MERCK) APPROVAL= AP YEAR= 1950 DISCONTINUED
NDA 008126 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (PHARMACIA AND UPJOHN) APPROVAL= AP YEAR= 1951 DISCONTINUED
NDA 008284 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (PANRAY) APPROVAL= AP YEAR= 1952 DISCONTINUED
NDA 080630 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 080776 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (HIKMA INTL PHARMS) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 080341 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (WHITEWORTH TOWN PLSN) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 083471 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (BARR) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 083536 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 080694 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (CHARTWELL MOLECULAR) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 084246 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (EVERYLIFE) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 009458 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (IMPAX LABS) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085677 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (WATSON LABS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085884 (pdf not found) INN (CORTISONE ACETATE) CORTISONE ACETATE (WATSON LABS) APPROVAL= AP YEAR= 1978 DISCONTINUED