e-Drug3D

815

cas 151319-34-5

CLASS

NERVOUS SYSTEM
HYPNOTIC
ANXIOLYTIC
ANTICONVULSANTS
MUSCLE RELAXANT
SEDATIVE
A NONBENZODIAZEPINE HYPNOTIC FROM THE PYRAZOLOPYRIMIDINE CLASS

ROUTE (list)

ORAL

PK parameters

F 30 PERCENT
Tmax 1 HOUR
VD 91 LITER (65 KILOGRAM)
Cl 195 LITER / HOUR (65 KILOGRAM)
PPB 60 PERCENT
t1/2 1 HOUR

MW 305.34
NB_atoms 23
XLogP 2.64
PSA 64.548
NB_HD 0
NB_HA 6
fsp3 0.18
Lipinski(0=no;1=yes) 1

FDA
NDA 020859 (pdf not found) INN (ZALEPLON) SONATA (PFIZER) APPROVAL= AP YEAR= 1999 NEWMOLECULARENTITY
NDA 077237 (pdf not found) INN (ZALEPLON) ZALEPLON (HIKMA) APPROVAL= AP YEAR= 2008
NDA 077238 (pdf not found) INN (ZALEPLON) ZALEPLON (NATCO PHARMA) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 077239 (pdf not found) INN (ZALEPLON) ZALEPLON (TEVA PHARMS) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 077505 (pdf not found) INN (ZALEPLON) ZALEPLON (CHARTWELL MOLECULAR) APPROVAL= AP YEAR= 2008
NDA 078095 (pdf not found) INN (ZALEPLON) ZALEPLON (UPSHER SMITH LABS) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 078706 (pdf not found) INN (ZALEPLON) ZALEPLON (UPSHER SMITH LABS) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 078829 (pdf not found) INN (ZALEPLON) ZALEPLON (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2008
NDA 078989 (pdf not found) INN (ZALEPLON) ZALEPLON (UNICHEM) APPROVAL= AP YEAR= 2008
NDA 078147 (pdf not found) INN (ZALEPLON) ZALEPLON (HIKMA PHARMS) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 090374 (pdf not found) INN (ZALEPLON) ZALEPLON (ORBION PHARMS) APPROVAL= AP YEAR= 2009