e-Drug3D

813

cas 34391-04-3

CLASS

RESPIRATORY SYSTEM
BETA2-ADRENERGIC BRONCHODILATOR
AGONIST
BETA-BLOCKERS

ROUTE (list)

INHALATION

PK parameters

t1/2 4.6 HOUR

TARGET BETA2-ADRENERGIC

PDB
2Y04 (TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND PARTIAL AGONIST SALBUTAMOL)

Ligand code = 68H (link to the list of PDB complexes)

Download experimental 3D coordinates of 68H with added hydrogens

MW 239.31
NB_atoms 17
XLogP 1.31
PSA 73.773
NB_HD 4
NB_HA 4
fsp3 0.54
Lipinski(0=no;1=yes) 1

FDA
NDA 020837 (label) INN (LEVALBUTEROL HYDROCHLORIDE) XOPENEX (HIKMA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 021730 (label) INN (LEVALBUTEROL TARTRATE) XOPENEX HFA (LUPIN) APPROVAL= AP YEAR= 2005
NDA 077756 (pdf not found) INN (LEVALBUTEROL HYDROCHLORIDE) LEVALBUTEROL HYDROCHLORIDE (IMPAX LABS INC) APPROVAL= AP YEAR= 2008
NDA 078309 (pdf not found) INN (LEVALBUTEROL HYDROCHLORIDE) LEVALBUTEROL HYDROCHLORIDE (MYLAN SPECIALITY LP) APPROVAL= AP YEAR= 2009
NDA 077800 (pdf not found) INN (LEVALBUTEROL HYDROCHLORIDE) LEVALBUTEROL HYDROCHLORIDE (PHARMOBEDIENT) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 078171 (pdf not found) INN (LEVALBUTEROL HYDROCHLORIDE) LEVALBUTEROL HYDROCHLORIDE (CIPLA) APPROVAL= AP YEAR= 2013
NDA 090297 (pdf not found) INN (LEVALBUTEROL HYDROCHLORIDE) LEVALBUTEROL HYDROCHLORIDE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2013
NDA 200875 (pdf not found) INN (LEVALBUTEROL HYDROCHLORIDE) LEVALBUTEROL HYDROCHLORIDE (TEVA PARENTERAL) APPROVAL= AP YEAR= 2014
NDA 203653 (pdf not found) INN (LEVALBUTEROL HYDROCHLORIDE) LEVALBUTEROL HYDROCHLORIDE (RITEDOSE CORP) APPROVAL= AP YEAR= 2016
NDA 207625 (pdf not found) INN (LEVALBUTEROL HYDROCHLORIDE) LEVALBUTEROL HYDROCHLORIDE (LUOXIN AUROVITAS) APPROVAL= AP YEAR= 2016
NDA 207628 (pdf not found) INN (LEVALBUTEROL HYDROCHLORIDE) LEVALBUTEROL HYDROCHLORIDE (LUOXIN AUROVITAS) APPROVAL= AP YEAR= 2017
NDA 207820 (pdf not found) INN (LEVALBUTEROL HYDROCHLORIDE) LEVALBUTEROL HYDROCHLORIDE (SUN PHARM) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 218770 (pdf not found) INN (LEVALBUTEROL HYDROCHLORIDE) LEVALBUTEROL HYDROCHLORIDE (MANKIND PHARMA) APPROVAL= AP YEAR= 2024 DISCONTINUED