e-Drug3D

810

cas 73573-87-2

CLASS

RESPIRATORY SYSTEM
BRONCHODILATOR
LONG-ACTING SELECTIVE BETA-2 ADRENERGIC RECEPTOR AGONIST
SYMPATHOMIMETIC

ROUTE (list)

INHALATION

PK parameters

F 61 PERCENT
Tmax 0.08 HOUR
VD 260 LITER (65 KILOGRAM)
Cl 84 LITER / HOUR
PPB 62.5 PERCENT
t1/2 13 HOUR

TARGET BETA-2 ADRENERGIC RECEPTOR

PDB
6H7K (ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND AGONIST FORMOTEROL)

Ligand code = FVN (link to the list of PDB complexes)

Download experimental 3D coordinates of FVN with added hydrogens

MW 344.40
NB_atoms 25
XLogP 2.22
PSA 90.923
NB_HD 4
NB_HA 6
fsp3 0.32
Lipinski(0=no;1=yes) 1

FDA
NDA 020831 (pdf not found) INN (FORMOTEROL FUMARATE) FORADIL (NOVARTIS) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 021279 (pdf not found) INN (FORMOTEROL FUMARATE) FORADIL (NOVARTIS) APPROVAL= AP YEAR= 2001 NEWAPPLICATION DISCONTINUED
NDA 021592 (pdf not found) INN (FORMOTEROL FUMARATE) FORADIL CERTIHALER (NOVARTIS) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 021929 (pdf not found) INN (BUDESONIDE ; FORMOTEROL FUMARATE DIHYDRATE) SYMBICORT (ASTRAZENECA) APPROVAL= AP YEAR= 2006
NDA 022007 (pdf not found) INN (FORMOTEROL FUMARATE) PERFOROMIST (VIATRIS SPECIALTY) APPROVAL= AP YEAR= 2007
NDA 022518 (pdf not found) INN (FORMOTEROL FUMARATE ; MOMETASONE FUROATE) DULERA (ORGANON LLC) APPROVAL= AP YEAR= 2010
NDA 208294 (pdf not found) INN (FORMOTEROL FUMARATE ; GLYCOPYRROLATE) BEVESPI AEROSPHERE (ASTRAZENECA) APPROVAL= AP YEAR= 2016
NDA 210595 (pdf not found) INN (ACLIDINIUM BROMIDE ; FORMOTEROL FUMARATE) DUAKLIR PRESSAIR (COVIS) APPROVAL= AP YEAR= 2019
NDA 212122 (pdf not found) INN (BUDESONIDE ; FORMOTEROL FUMARATE ; GLYCOPYRROLATE) BREZTRI AEROSPHERE (ASTRAZENECA AB) APPROVAL= AP YEAR= 2020
NDA 091141 (pdf not found) INN (FORMOTEROL FUMARATE) FORMOTEROL FUMARATE (TEVA PHARMS USA INC) APPROVAL= AP YEAR= 2021
NDA 215078 (pdf not found) INN (FORMOTEROL FUMARATE) FORMOTEROL FUMARATE (ALEMBIC) APPROVAL= AP YEAR= 2021
NDA 211699 (pdf not found) INN (BUDESONIDE ; FORMOTEROL FUMARATE DIHYDRATE) BREYNA (MYLAN) APPROVAL= AP YEAR= 2022
NDA 215053 (pdf not found) INN (FORMOTEROL FUMARATE) FORMOTEROL FUMARATE (LUPIN) APPROVAL= AP YEAR= 2022
NDA 215621 (pdf not found) INN (FORMOTEROL FUMARATE) FORMOTEROL FUMARATE (WILSHIRE PHARMS INC) APPROVAL= AP YEAR= 2022
NDA 216486 (pdf not found) INN (FORMOTEROL FUMARATE) FORMOTEROL FUMARATE (RITEDOSE CORP) APPROVAL= AP YEAR= 2022
NDA 215883 (pdf not found) INN (FORMOTEROL FUMARATE) FORMOTEROL FUMARATE (MANKIND PHARMA) APPROVAL= AP YEAR= 2023
NDA 216579 (pdf not found) INN (BUDESONIDE ; FORMOTEROL FUMARATE) SYMBICORT AEROSPHERE (ASTRAZENECA) APPROVAL= AP YEAR= 2023
NDA 216426 (pdf not found) INN (FORMOTEROL FUMARATE) FORMOTEROL FUMARATE (LEXENPHARM) APPROVAL= AP YEAR= 2024
NDA 218304 (pdf not found) INN (FORMOTEROL FUMARATE) FORMOTEROL FUMARATE (MICRO LABS) APPROVAL= AP YEAR= 2024
NDA 215907 (pdf not found) INN (FORMOTEROL FUMARATE) FORMOTEROL FUMARATE (DR REDDYS) APPROVAL= AP YEAR= 2025
NDA 218308 (pdf not found) INN (FORMOTEROL FUMARATE) FORMOTEROL FUMARATE (DEVA HOLDING AS) APPROVAL= AP YEAR= 2025