e-Drug3D

806

cas 131918-61-1

CLASS

METABOLISM
PARATHYROID HORMONE REGULATOR
VITAMIN D3 RECEPTOR (VDR) AGONIST
CALCITRIOL ANALOG
TREATMENT OF SECONDARY HYPERPARATHYROIDISM

ROUTE (list)

INTRAVENOUS ORAL INJECTION

PK parameters

F 79 PERCENT
VD 34 LITER
Cl 1.49 LITER / HOUR
PPB 99.8 PERCENT
t1/2 5 HOUR

MW 416.62
NB_atoms 30
XLogP 5.56
PSA 60.046
NB_HD 3
NB_HA 3
fsp3 0.78
Lipinski(0=no;1=yes) 0

FDA
NDA 020819 (label) INN (PARICALCITOL) ZEMPLAR (ABBVIE) APPROVAL= AP YEAR= 1998
NDA 021606 (label) INN (PARICALCITOL) ZEMPLAR (ABBVIE) APPROVAL= AP YEAR= 2005
NDA 091108 (pdf not found) INN (PARICALCITOL) PARICALCITOL (SANDOZ) APPROVAL= AP YEAR= 2011
NDA 090829 (pdf not found) INN (PARICALCITOL) PARICALCITOL (TEVA PHARMS USA) APPROVAL= AP YEAR= 2013
NDA 091583 (pdf not found) INN (PARICALCITOL) PARICALCITOL (TEVA PHARMS USA) APPROVAL= TA YEAR= 2013
NDA 091412 (pdf not found) INN (PARICALCITOL) PARICALCITOL (CHARTWELL RX) APPROVAL= AP YEAR= 2014
NDA 201657 (label) INN (PARICALCITOL) PARICALCITOL (HOSPIRA) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 202124 (pdf not found) INN (PARICALCITOL) PARICALCITOL (RISING) APPROVAL= AP YEAR= 2014
NDA 202539 (pdf not found) INN (PARICALCITOL) PARICALCITOL (BIONPHARMA) APPROVAL= AP YEAR= 2014
NDA 205917 (label) INN (PARICALCITOL) PARICALCITOL (HIKMA PHARMS) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 204910 (pdf not found) INN (PARICALCITOL) PARICALCITOL (CAPLIN) APPROVAL= AP YEAR= 2016
NDA 206710 (pdf not found) INN (PARICALCITOL) PARICALCITOL (LOTUS PHARM CO LTD) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 204327 (pdf not found) INN (PARICALCITOL) PARICALCITOL (AMNEAL PHARMS) APPROVAL= AP YEAR= 2016
NDA 207174 (label) INN (PARICALCITOL) PARICALCITOL (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2016
NDA 207672 (pdf not found) INN (PARICALCITOL) PARICALCITOL (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2016
NDA 204948 (pdf not found) INN (PARICALCITOL) PARICALCITOL (MARKSANS PHARMA) APPROVAL= AP YEAR= 2016
NDA 206699 (pdf not found) INN (PARICALCITOL) PARICALCITOL (AMNEAL PHARMS CO) APPROVAL= AP YEAR= 2017
NDA 203897 (pdf not found) INN (PARICALCITOL) PARICALCITOL (RISING) APPROVAL= AP YEAR= 2017
NDA 207692 (pdf not found) INN (PARICALCITOL) PARICALCITOL (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 205982 (pdf not found) INN (PARICALCITOL) PARICALCITOL (EUGIA PHARMA) APPROVAL= AP YEAR= 2018