e-Drug3D

799

cas 139264-17-8

CLASS

NERVOUS SYSTEM
ANTIMIGRAINE
ANTI-INFLAMMATORY AGENTS
SELECTIVE SEROTONIN 5-HYDROXYTRYPTAMINE 1B/1D RECEPTOR AGONISTS
VASOCONSTRICTOR AGENTS

ROUTE (list)

ORAL NASAL

PK parameters

F 40 PERCENT
Tmax 1.5 HOUR
VD 455 LITER (65 KILOGRAM)
Cl 122.8 LITER / HOUR
PPB 25 PERCENT
t1/2 3 HOUR

MW 287.36
NB_atoms 21
XLogP 1.92
PSA 62.112
NB_HD 2
NB_HA 5
fsp3 0.44
Lipinski(0=no;1=yes) 1

FDA
NDA 020768 (label) INN (ZOLMITRIPTAN) ZOMIG (IPR) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 021231 (label) INN (ZOLMITRIPTAN) ZOMIG-ZMT (ASTRAZENECA) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 021450 (label) INN (ZOLMITRIPTAN) ZOMIG (AMNEAL) APPROVAL= AP YEAR= 2003
NDA 201779 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2013
NDA 202078 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (APOTEX INC) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 202476 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (APOTEX INC) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 202560 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2013
NDA 202890 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (ZYDUS PHARMS USA INC) APPROVAL= AP YEAR= 2013
NDA 203186 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (NATCO PHARMA USA) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 090861 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (ANI PHARMS) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 202279 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (JUBILANT GENERICS) APPROVAL= AP YEAR= 2014
NDA 203476 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (SUN PHARMA GLOBAL) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 204284 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (INVAGEN PHARMS) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 202956 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (JUBILANT GENERICS) APPROVAL= AP YEAR= 2015
NDA 203772 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (MACLEODS PHARMS LTD) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 204232 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (ALEMBIC) APPROVAL= AP YEAR= 2015
NDA 204336 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (MACLEODS PHARMS LTD) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 204041 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (AJANTA PHARMA LTD) APPROVAL= AP YEAR= 2016
NDA 207021 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2016
NDA 205074 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (ALEMBIC) APPROVAL= AP YEAR= 2016
NDA 206973 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2017
NDA 207867 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (PLD ACQUISITIONS LLC) APPROVAL= AP YEAR= 2017
NDA 203019 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (ZYDUS PHARMS) APPROVAL= AP YEAR= 2018
NDA 202855 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (RISING) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 203726 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (ORBION PHARMS) APPROVAL= AP YEAR= 2019
NDA 212469 (pdf not found) INN (ZOLMITRIPTAN) ZOLMITRIPTAN (PADAGIS ISRAEL) APPROVAL= AP YEAR= 2021