e-Drug3D

797

cas 121679-13-8

CLASS

NERVOUS SYSTEM
ANTIMIGRAINE
SELECTIVE SEROTONIN AGONISTS
VASOCONSTRICTOR AGENTS

ROUTE (list)

ORAL

PK parameters

F 70 PERCENT
Tmax 2.5 HOUR
VD 170 LITER
Cl 25.7 LITER / HOUR (65 KILOGRAM)
PPB 30 PERCENT
t1/2 6 HOUR

MW 335.47
NB_atoms 23
XLogP 2.07
PSA 69.192
NB_HD 2
NB_HA 5
fsp3 0.53
Lipinski(0=no;1=yes) 1

FDA
NDA 020763 (pdf not found) INN (NARATRIPTAN HYDROCHLORIDE) AMERGE (GLAXOSMITHKLINE LLC) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 090288 (pdf not found) INN (NARATRIPTAN HYDROCHLORIDE) NARATRIPTAN (CHARTWELL RX) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 090381 (pdf not found) INN (NARATRIPTAN HYDROCHLORIDE) NARATRIPTAN (HIKMA) APPROVAL= AP YEAR= 2010
NDA 078751 (pdf not found) INN (NARATRIPTAN HYDROCHLORIDE) NARATRIPTAN (ANI PHARMS) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 091326 (pdf not found) INN (NARATRIPTAN HYDROCHLORIDE) NARATRIPTAN (PADAGIS US) APPROVAL= AP YEAR= 2010
NDA 091373 (pdf not found) INN (NARATRIPTAN HYDROCHLORIDE) NARATRIPTAN (APOTEX CORP) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 091552 (pdf not found) INN (NARATRIPTAN HYDROCHLORIDE) NARATRIPTAN (SUN PHARM INDS LTD) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 200502 (pdf not found) INN (NARATRIPTAN HYDROCHLORIDE) NARATRIPTAN (HERITAGE) APPROVAL= AP YEAR= 2011
NDA 091441 (pdf not found) INN (NARATRIPTAN HYDROCHLORIDE) NARATRIPTAN (ORBION PHARMS) APPROVAL= AP YEAR= 2012
NDA 202431 (pdf not found) INN (NARATRIPTAN HYDROCHLORIDE) NARATRIPTAN (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2012 DISCONTINUED