e-Drug3D

773

cas 91374-21-9

CLASS

NERVOUS SYSTEM
ANTIDYSKINETICS
ANTIPARKINSON AGENTS
NON-ERGOLINE DOPAMINE AGONISTS

ROUTE (list)

ORAL

PK parameters

F 55 PERCENT
Tmax 1.5 HOUR
VD 487.5 LITER (65 KILOGRAM)
Cl 47 LITER / HOUR
PPB 40 PERCENT
t1/2 6 HOUR

MW 260.37
NB_atoms 19
XLogP 2.85
PSA 36.57
NB_HD 1
NB_HA 3
fsp3 0.56
Lipinski(0=no;1=yes) 1

FDA
NDA 020658 (label) INN (ROPINIROLE HYDROCHLORIDE) REQUIP (GLAXOSMITHKLINE LLC) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 022008 (label) INN (ROPINIROLE HYDROCHLORIDE) REQUIP XL (GLAXOSMITHKLINE LLC) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 077460 (label) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (COSETTE) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 077852 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 078110 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (PRINSTON INC) APPROVAL= AP YEAR= 2008
NDA 078230 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 078881 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (PHARMOBEDIENT) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 079050 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 2008
NDA 090411 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (ZYDUS LIFESCIENCES) APPROVAL= AP YEAR= 2009
NDA 090135 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2010
NDA 090429 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (ALEMBIC LTD) APPROVAL= AP YEAR= 2010
NDA 079165 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (MLV) APPROVAL= AP YEAR= 2012
NDA 201576 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (DR REDDYS LABS LTD) APPROVAL= AP YEAR= 2012
NDA 091395 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 2012
NDA 079229 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (ORBION PHARMS) APPROVAL= AP YEAR= 2012
NDA 090869 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 2012
NDA 200431 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (WATSON LABS INC) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 200462 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (MYLAN PHARMS INC) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 201047 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (SANDOZ INC) APPROVAL= AP YEAR= 2012
NDA 202786 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (ALEMBIC) APPROVAL= AP YEAR= 2013
NDA 204022 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2017
NDA 204413 (pdf not found) INN (ROPINIROLE HYDROCHLORIDE) ROPINIROLE HYDROCHLORIDE (PRINSTON INC) APPROVAL= AP YEAR= 2022