e-Drug3D

767

REMIFENTANIL

INN
REMIFENTANIL

cas 132875-61-7

CLASS

NERVOUS SYSTEM
ANALGESICS, OPIOID

ROUTE (list)

INJECTION

ATC code

N01AH06

PK parameters

VD 22.7 LITER (65 KILOGRAM)
Cl 156 LITER / HOUR (65 KILOGRAM)
PPB 70 PERCENT
t1/2 0.25 HOUR

Target

TARGET MU-TYPE OPIOID RECEPTOR

DrugCentral

Mu-type opioid receptor UNIPROT P35372 OPRM1

Download SDF file

methyl 1-(3-methoxy-3-oxopropyl)-4-(phenyl-propanoylamino)piperidine-4-carboxylate

Formula:
C20H28N2O5

Calculated chemical properties:

MW 376.44
NB_atoms 27
XLogP 2.00
PSA 68.871
NB_HD 0
NB_HA 7
fsp3 0.55
Lipinski(0=no;1=yes) 1

FDA
NDA 020630 (pdf not found) INN (REMIFENTANIL HYDROCHLORIDE) ULTIVA (MYLAN INSTITUTIONAL) APPROVAL= AP YEAR= 1996
NDA 206223 (pdf not found) INN (REMIFENTANIL HYDROCHLORIDE) REMIFENTANIL HYDROCHLORIDE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2018
NDA 210594 (pdf not found) INN (REMIFENTANIL HYDROCHLORIDE) REMIFENTANIL HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 2020
NDA 215635 (pdf not found) INN (REMIFENTANIL HYDROCHLORIDE) REMIFENTANIL HYDROCHLORIDE (NIVAGEN PHARMS INC) APPROVAL= AP YEAR= 2024