e-Drug3D

760

cas 144060-53-7

CLASS

METABOLISM
ANTIGOUT
CHRONIC MANAGEMENT OF HYPERURICEMIA IN PATIENTS WITH GOUT
XANTHINE OXIDASE INHIBITOR
DECREASES SERUM URIC ACID

ROUTE (list)

ORAL

PK parameters

F 49 PERCENT
Tmax 1.25 HOUR
VD 50 LITER
Cl 5.3 LITER / HOUR (EQN)
PPB 99.2 PERCENT
t1/2 6.5 HOUR

TARGET XANTHINE OXIDASE

PDB
1N5X (XANTHINE DEHYDROGENASE FROM BOVINE MILK WITH INHIBITOR TEI-6720 BOUND)

Ligand code = TEI (link to the list of PDB complexes)

Download experimental 3D coordinates of TEI with added hydrogens

MW 315.37
NB_atoms 22
XLogP 2.39
PSA 72.468
NB_HD 0
NB_HA 5
fsp3 0.31
Lipinski(0=no;1=yes) 1

FDA
NDA 021856 (pdf not found) INN (FEBUXOSTAT) ULORIC (TAKEDA PHARMS USA) APPROVAL= AP YEAR= 2009
NDA 211339 (pdf not found) INN (FEBUXOSTAT) FEBUXOSTAT (BEIJING SL PHARMA CO LTD) APPROVAL= TA YEAR= 2018
NDA 205385 (pdf not found) INN (FEBUXOSTAT) FEBUXOSTAT (PHARMOBEDIENT) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 205421 (pdf not found) INN (FEBUXOSTAT) FEBUXOSTAT (ALEMBIC) APPROVAL= AP YEAR= 2019
NDA 205414 (pdf not found) INN (FEBUXOSTAT) FEBUXOSTAT (HIKMA) APPROVAL= AP YEAR= 2019
NDA 210461 (pdf not found) INN (FEBUXOSTAT) FEBUXOSTAT (MSN) APPROVAL= AP YEAR= 2019
NDA 205467 (pdf not found) INN (FEBUXOSTAT) FEBUXOSTAT (SUN PHARM) APPROVAL= AP YEAR= 2019
NDA 210292 (pdf not found) INN (FEBUXOSTAT) FEBUXOSTAT (INDOCO) APPROVAL= AP YEAR= 2019
NDA 213069 (pdf not found) INN (FEBUXOSTAT) FEBUXOSTAT (SUNSHINE) APPROVAL= AP YEAR= 2020
NDA 205374 (pdf not found) INN (FEBUXOSTAT) FEBUXOSTAT (DR REDDYS) APPROVAL= AP YEAR= 2020
NDA 212924 (pdf not found) INN (FEBUXOSTAT) FEBUXOSTAT (ALKEM LABS LTD) APPROVAL= AP YEAR= 2021
NDA 206266 (pdf not found) INN (FEBUXOSTAT) FEBUXOSTAT (PRINSTON INC) APPROVAL= AP YEAR= 2022
NDA 207293 (pdf not found) INN (FEBUXOSTAT) FEBUXOSTAT (MACLEODS PHARMS LTD) APPROVAL= AP YEAR= 2023
NDA 205443 (pdf not found) INN (FEBUXOSTAT) FEBUXOSTAT (ZYDUS LIFESCIENCES) APPROVAL= AP YEAR= 2023
NDA 211837 (pdf not found) INN (FEBUXOSTAT) FEBUXOSTAT (TORRENT) APPROVAL= AP YEAR= 2023 DISCONTINUED
NDA 210741 (pdf not found) INN (FEBUXOSTAT) FEBUXOSTAT (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2023
NDA 205406 (pdf not found) INN (FEBUXOSTAT) FEBUXOSTAT (LUPIN LTD) APPROVAL= AP YEAR= 2024 DISCONTINUED